بررسی آگاهی، میزان و نحوه مصرف اسیدفولیک در بارداری و پیش بارداری: یک مرور نظام‌مند و متآنالیز

نوع مقاله: مروری

نویسندگان

1 مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران. دانشجوی دکترای تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شاهرود، شاهرود، ایران

2 استاد گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شاهرود، شاهرود، ایران.

3 دانشجوی دکترای تخصصی بهداشت باروری، مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: اسیدفولیک، یک ماده مغذی مهم برای حفظ و ارتقاء سلامت محسوب می‌شود و کمبود اسیدفولیک در دوران بارداری احتمال سقط خودبه‌خودی جنین، نقص لوله عصبی، پره‌اکلامپسی، دکولمان جفت، زایمان زودرس، وزن کم هنگام تولد و کم‌خونی را افزایش می‌دهد و بسیاری از موارد ذکر شده، از طریق افزایش دریافت اسیدفولیک در بارداری و پیش بارداری قابل پیشگیری است. مطالعه حاضر با هدف تعیین سطح آگاهی و میزان مصرف اسیدفولیک در بارداری و پیش بارداری به‌روش متاآنالیز انجام شد.
روش‌کار: در این مطالعه مرور سیستماتیک و فراتحلیل (متاآنالیز) به منظور یافتن مقالات مرتبط، مجلات فارسی و انگلیسی زبان نمایه شده در SID، Iranmedx، Irandoc، Magiran، Scopus و Pubmed با استفاده از کلید واژه‌های Mesh تا اول مرداد سال 1397 مورد جستجو قرار گرفتند. جهت بررسی ناهمگنی در مطالعات از شاخص I2 استفاده شد. داده‌ها با روش متاآنالیز و با استفاده از مدل اثرات تصادفی مورد تجزیه و تحلیل قرار گرفتند.
یافته­ها: از بین 2366 مقاله یافت شده در جستجوی اولیه، تعداد 16 مطالعه برای مرور سیستماتیک و متاآنالیز انتخاب گردید. در متاآنالیز انجام شده با توجه به مدل اثرات تصادفی به‌دلیل میزان ناهمگنی 97%، حیطه شنیدن نام اسیدفولیک توسط زنان 8/84% (1/90-5/77)، آگاهی زنان از نقش اسیدفولیک 2/37% (1/48-5/27)، آگاهی از زمان مصرف اسیدفولیک 3/27% (3/39-9/17)، آگاهی از دوز صحیح مصرف اسیدفولیک 2/75% (2/84-3/63)، مصرف اسیدفولیک در بارداری 74% (6/81-2/65)، مصرف اسیدفولیک در قبل از بارداری 3/18% (9/25-6/12)، مصرف منظم 47% (3/90-8/7) و مصرف نامنظم اسیدفولیک در مجموع 9/40% (7/82-1/9) برآورد شد.
نتیجه­گیری: سطح آگاهی زنان سنین باروری نسبت به مکمل اسیدفولیک و نقش ارزنده آن در بارداری مطلوب نمی‌باشد. از آنجا که پرسنل بهداشتی به‌عنوان مهم‌ترین منبع کسب اطلاعات در زمینه مصرف اسیدفولیک شناخته شده‌اند، لذا اهتمام بیشتر آنان در این رابطه کمک شایانی به افزایش سطح آگاهی زنان می‌نماید.

کلیدواژه‌ها


عنوان مقاله [English]

The level of Knowledge and consumption of Folic Acid in pregnancy and pre-conception: A Systematic Review and Meta-analysis

نویسندگان [English]

  • Fatemeh Ghaffari Sardasht 1
  • Afsaneh Keramat 2
  • Morvarid Irani 3
1 Nursing and Midwifery Care Research Center, Mashhad university of medical sciences, Mashhad, Iran. PhD student in Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran
2 Professor, Department of Midwifery, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran.
3 PhD student in Reproductive Health, Nursing and Midwifery Care Research Center, Mashhad university of medical sciences, Mashhad, Iran.
چکیده [English]

ntroduction: Folic acid is an important nutrient for maintaining and improving health and its deficiency during pregnancy increase the risk of spontaneous abortion, neural tube defects, preeclampsia, placental abruption, preterm labor, low birth weight and anemia. These risks can be prevented by increasing folic acid intake during pregnancy and pre-conception. Therefore, this study was performed with aim to determine the level of knowledge and consumption of Folic acid in pregnancy and pre-conception through meta-analysis.
Methods: In this systematic review and meta-analysis study, for finding the related articles, the Persian and English journals which were indexed in databases of SID, Iranmedx, Irandoc, Magiran, Scopus, and PubMed were searched with Mesh keywords up to August, 2018. I2 index was used to assess the heterogeneity in the studies. Data were analyzed by meta-analysis method using random effects model.
Results: Of the 2366 articles found in the primary search, 16 articles were selected for systematic review and meta-analysis. In the meta-analysis, according to the random effects model due to heterogeneity 97% , these results were estimated: hearing the name of folic acid by women in 84.8% (77.5-90.1), knowledge of women from the role of folic acid in 37.2% (27.5-48.1), knowledge of the time of taking folic acid in 27.3% (17.9-39.3), knowledge of the correct dose of folic acid in 75.2% (63.3-84.2), use of Folic acid during pregnancy in 74% (65.2-81.6), use of folic acid in pre-pregnancy in 18.3 % (12.6-25.9), regular consumption in 47% (7.8-90.3), and irregular consumption of folic acid in 40.9% (9.1-82.7).
Conclusion: The level of knowledge of women at reproductive age about folic acid complementary and its valuable role in pregnancy is not desirable. Since health personnel are the most important source of information on the use of folic acid, so they have to work more efforts in this regard to increase the level of women's knowledge.

کلیدواژه‌ها [English]

  • folic acid
  • Function
  • Iran
  • Knowledge
  • Meta-analysis
  • Reproductive age
  • Systematic review
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