تأثیر تمرینات ترکیبی (هوازی- مقاومتی) بر آمادگی هوازی، قدرت عضلانی، گلوکز خون، مقاومت به انسولین و سطح سرمی بتااندورفین زنان دیابتی نوع دو

نوع مقاله: اصیل پژوهشی

نویسندگان

1 کارشناس ارشد‏ فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران.‏

2 دانشیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران.‏

3 استادیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران.

چکیده

مقدمه: دیابت، شایع‌ترین بیماری ناشی از اختلالات متابولیسمی و یکی از مهم‌ترین مشکلات بهداشت عمومی است. دیابت، مسئول 9% کل مرگ­های جهان می­باشد و می­تواند در درازمدت منجر به نوروپاتی، نفروپاتی، رتینوپاتی و بیماری قلبی گردد، لذا مطالعه حاضر با هدف بررسی اثر تمرین ترکیبی (هوازی- مقاومتی) بر سطوح بتااندورفین و تأثیر آن بر گیرنده µ در سطح عضله اسکلتی برای کاهش گلوکز و مقاومت به انسولین زنان غیرفعال دیابتی نوع دو انجام شد.
روش­کار: این مطالعه کارآزمایی بالینی تصادفی شده در سال 1394 بر روی 18 نفر از زنان غیرفعال دیابتی نوع دو با محدوده سنی 50-40 سال انجام شد. آزمودنی­ها به‌طور تصادفی در دو گروه تجربی و کنترل قرار گرفتند. برنامه تمرینی به‌مدت 8 هفته و 3 روز در هفته انجام شد. برنامه تمرین هوازی شامل 20 دقیقه فعالیت ایروبیک و برنامه تمرین قدرتی توسط افراد گروه تجربی انجام شد. 48 ساعت قبل و بعد از مداخله تمرینی، نمونه خونی آزمودنی‌ها به‌منظور برآورد مقادیر سرمی بتااندورفین، گلوکز و انسولین جمع‌آوری شد. تجزیه و تحلیل داده­ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون­های تی دانشجویی وابسته و مستقل و آزمون­های ویلکاکسون و یومن‌ویتنی انجام شد. میزان p کمتر از 05/0 معنی­دار در نظر گرفته شد.
یافته­ها: تمرین ترکیبی باعث افزایش معنی­دار اکسیژن مصرفی اوج، قدرت، سطح سرمی بتااندورفین و کاهش معنی­دار گلوکز و مقاومت به انسولین گردید (05/0≥p).
نتیجه­گیری: تمرینات ترکیبی، شاخص گلایسمیک را کاهش و بتااندورفین را افزایش می‌دهد که می­تواند اثر مطلوبی در کاهش عوامل خطرزا در بیماران مبتلا به دیابت نوع دو داشته باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of combined aerobic and resistance training on aerobic fitness, strength, beta-endorphin, blood glucose level, and insulin resistance in women with type II diabetes mellitus

نویسندگان [English]

  • Malihe Esmaeili 1
  • Nahid Bijeh 2
  • Mahdi Ghahremani Moghadam 3
1 M.Sc.‎ in Sport Physiology, School of Physical Education and Sport Sciences, Ferdowsi ‎University of Mashhad, Mashhad, Iran.‎
2 Associate Professor, Department of Sport Physiology, School of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
3 Assistant Professor, Department of Sport Physiology, School of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
چکیده [English]

Introduction:Diabetes mellitus is one of the most common metabolic disorders and important public health problems. This disease accounts for 9% of all mortalities in the world and can lead to neuropathy, nephropathy, retinopathy, and cardiac disease in the long term. Regarding this, the present study aimed to assess the effect of combined aerobic and resistance training on beta-endorphin level and its influence on μ receptor in skeletal muscles for reducing glucose and insulin resistance levels in sedentary women with type II diabetes mellitus.
Methods: This randomized clinical trial was performed on 18 sedentary women with type II diabetes mellitus aged 40-50 years in 2015. The subjects were randomly divided into intervention and control groups. The exercise program was conducted for 8 weeks, three sessions a week. Each session included a 20-minute aerobic training, in addition to a strength training program. Blood samples were collected to investigate the serum levels of β-endorphin, glucose, and insulin 48 h before and after the intervention. Data analysis was performed in SPSS software (version 16) using Student’s, paired sample, and independent t-tests for the normal data and Wilcoxon and Mann-Whitney U tests for abnormal data to estimate the intra-group and inter-group differences, respectively. P-value less than 0.05 was considered statistically significant.
Results: The results indicated that our combined training significantly increased maximal oxygen uptake, strength, and serum level of β-endorphin, and decreased the glucose and insulin-resistance levels (P≤0.05).
Conclusion: This study showed that the combined training declined glycemic index and augmented β-endorphin level. Consequently, this intervention could make a desirable effect on the reduction of risk factors in women with type II diabetes mellitus.

کلیدواژه‌ها [English]

  • Combined exercise
  • β-endorphin
  • Glucose
  • Insulin-resistance
  • Type II diabetes mellitus
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