مروری بر گیاهان ضد تریکومونا واژینالیس و اثرات درمانی آنها

نوع مقاله: مروری

نویسندگان

1 استادیار گروه مامایی، مرکز تحقیقات مراقبت مبتنی بر شواهد، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 مربی گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه آزاد اسلامی واحد قوچان، قوچان، ایران.

3 استادیار گروه زنان و مامایی، مرکز تحقیقات سلامت زنان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 دانشجوی دکترای تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: واژینیت تریکومونایی، شایع‌ترین بیماری غیر‌ویروسی قابل انتقال از راه جنسی و مترونیدازول مؤثرترین داروی آن است که همانند سایر داروهای صناعی دارای اثرات نامطلوب می­باشد. از آنجا که گیاهان دارویی عوارض جانبی کمتر و مقبولیت بیشتری در میان اکثر مردم دارند، مطالعه حاضر با هدف مروری بر گیاهان ضد تریکوموناس واژینالیس و اثرات درمانی آنها انجام شد.
روش‌کار: در این مطالعه مروری، بانک­های اطلاعاتی Scopus، Pubmed، Medline، Google Scholar، SID، Iran Medex و Magiran توسط کلید واژه­هایی مانند tricomona vaginalis،complementary و herbal medicine و معادل فارسی آنها نظیر تریکوموناس واژینالیس، گیاهان دارویی و درمان­های مکمل، در فاصله سال‌های 2017-1976 برای شناسایی مقالات مرتبط مورد جستجو قرار گرفتند. تمام مطالعات کارآزمایی in vivo و in vitro وارد مطالعه شدند. در جستجوی اولیه 120 مقاله یافت شد که در نهایت 25 مقاله مورد نقد و بررسی قرار گرفتند.
یافته‌ها: مطالعات بررسی شده در این مرور، بیان‌گر مؤثر بودن برخی ترکیبات گیاهی (آویشن شیرازی، سیر اسطوخودوس، اکالیپتوس، مورد) بر مهار رشد انگل تریکوموناس واژینالیس بودند، اما مطالعات انسانی بیشتر برای کاربردی شدن آنان در درمان واژینیت تریکومونایی مورد نیاز است.
نتیجه‌گیری: علی‌رغم اثرات مفیدگیاهان دارویی در درمان تریکومونا واژینالیس، از آنجا که عمده مطالعات in vitro بودند، کاربرد این گیاهان نیازمند مطالعات in vivo بیشتری است تا گامی مؤثر در جهت شناسایی هرچه بیشتر درمان‌های طبیعی به عنوان روش کم‌هزینه، کم‌خطر و در دسترس برداشته شود، لذا استفاده از نتایج این مطالعه باید با احتیاط صورت گیرد.

کلیدواژه‌ها


عنوان مقاله [English]

Review of anti-Trichomonas vaginalis herbs and their therapeutic effects

نویسندگان [English]

  • Fatemeh Zahra Karimi 1
  • Mohadese Bakhshi 2
  • Salme Dadgar 3
  • Nahid Maleki-Saghooni 4
1 Assistant Professor, Evidence-based Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Instructor, Department of Midwifery, School of Nursing and Midwifery, Islamic Azad University, Quchan Branch, Quchan, Iran.
3 Assistant Professor, Department of Obstetrics and Gynecology, Women Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
4 PhD Student of Reproductive Health, Student Research Committee, school of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction and Objectives: Trichomonas vaginitis is the most common non-viral disease transmitted through sexual contact. Metronidazole is the most effective medication that has the same adverse effects as other synthetic drugs. Since medicinal plants have less side effects and more popularity among most people, this study was conducted to review the effects of anti-trichomonas vaginalis plants and their therapeutic effects.
Materials and Methods: Persian and English databases, including PubMed, Medline, Scopus, Google Scholar, SID, IranMedex, and Magiran were searched for articles published between 1976 and 2017 using keywords such as ‘Trichomonas vaginalis’, ‘complementary therapies’ and ‘medicinal plants’ and their Persian equivalents. All the relevant in vivo and in vitro trials were included in the study. Overall, 120 papers were retrieved, 25 of which were critically reviewed.
Results: The articles reviewed in this study showed that some herbal compounds (e.g., Zataria multiflora Boiss, Allium staivum, Lavandula stoechas, Eucalyptus, and Myrtus communis)are effective in inhibiting the growth of Trichomonas vaginalis, but further human studies are needed to apply them to the treatment of Trichomonas vaginitis.
Conclusion: In spite of the beneficial effects of medicinal herbs on the treatment of Trichomonas vaginitis, since most of the studies were in vitro, the application of these plants requires more in vivo studies to take an effective step towards recognizing natural, low-cost, low-risk, and more accessible treatments.Therefore, the results of this study should be used with caution.

کلیدواژه‌ها [English]

  • Trichomonas vaginalis
  • Medicinal Plants
  • Complementary therapies
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