The effect of black cohosh along with misoprostol compared to misoprostol alone on cervical preparation before hysteroscopy in postmenopausal women: A randomized clinical trial study

Document Type : Original Article

Authors

1 Resident, Department of Obstetrics and Gynecology, Preventative Gynecology Diseases Research Center, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Assistant Professor, Department of Obstetrics and Gynecology, Preventative Gynecology Diseases Research Center, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

10.22038/ijogi.2024.80671.6119

Abstract

Introduction: Considering the effect of black cohosh in reducing the symptoms of premenstrual syndrome, breast cancer, migraine and infertility, and due to the lack of studies in this field, the present study was conducted with aim to comparatively investigate the effect of black cohosh plant root with on cervical preparation before hysteroscopy in postmenopausal women.
Methods: In this clinical trial study, all postmenopausal women who referred to Mahdieh Hospital for hysteroscopy during 2022-2023 were randomly divided into two groups. The first group received 200 micrograms of misoprostol 6-8 hours before the operation, and the second group in addition to 200 micrograms of misoprostol received 80 mg of black cohosh 6-8 hours before the operation. Complications of hysteroscopy, including pseudocanal, bleeding, and cervical rupture were also investigated and analyzed. After the operation, the patient's pain level was assessed based on the pain, nausea, vomiting, cramping, and shivering scales. Data analysis was performed using SPSS software (version 22).  P<0.05 was considered significant.
Results: The mean dilator size was higher in the intervention group compared to the other group, which was statistically significant (p<0.001). The frequency of severe pain was higher in the control group compared to the intervention group, while the frequency of mild and moderate pain in the intervention group was higher compared to the control group (p=0.01). The mean bleeding was higher in the control group compared to the intervention group, which was statistically significant (p=0.001), while no significant relationship was observed between the two groups in terms of complications such as analgesic use, cervical and uterine rupture, and pseudocanal (p>0.05).
Conclusion: Using black cohosh in patients can lead to a reduction in pain intensity and decrease in bleeding and complications in patients.

Keywords

Main Subjects

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 9
November 2024
Pages 20-28

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