The effect of six weeks aerobic training on body composition and serum level of IL-10 in middle-aged obese females

Document Type : Original Article


1 Assistant professor, Department of Exercise Physiology, School of Physical Education and Exercise Sciences, Islamshahr Branch, Islamic Azad University, Tehran, Iran

2 Assistant professor, Department of Exercise Physiology, School of Human Sciences, Saveh Branch, Islamic Azad University, Saveh, Iran.


Introduction: Interleukin 10 (IL-10) is an anti-inflammatory cytokine that its levels decrease in the presence of obesity and related diseases. Due to the lack of sufficient studies in this regard on healthy or patient obese women; this study was performed with aim to determine the effect of short term aerobic training on serum IL-10 in obese women.
Methods: This study was performed in summer 2016 on 30 sedentary middle-aged obese females aged 30-40 years (30≤BMI≤36 kg/m2) in Tehran, Iran. Subjects were divided into experimental (n=15) and control (n=15) groups. Experimental group underwent an aerobic training program for 6 weeks, 3 sessions per week with 30-45 minutes at 60 to 75% of the heart rate max. Abdominal obesity and other anthropometrical markers. as well serum IL-10 were measured at 48 hours before and after exercise intervention. Data were analyzed by SPSS software (version 15) and independent-t and dependent-t tests. P<0.05 was considered significant.
Results: Significant increase were observed in body weight, BMI, body fat percentage and abdominal obesity in experimental group (p<0.05). Also, serum IL-10 level significantly increased in exercise group (p = 0.001).
Conclusion: Short term aerobic training with moderate to high intensity leads to decreased obesity determinative indexes and increased serum IL-10 in obese females.


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