Menstrual pattern in women with Multiple Sclerosis

Document Type : Original Article

Authors

1 PhD student in Reproductive Health, Islamic Azad University, Mashhad Branch, Mashhad, Iran.

2 PhD student in Reproductive Health, Instructor of Midwifery group, Islamic Azad University, Mashhad Branch, Mashhad, Iran.

3 Associated Professor, Department of Neurology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 Phd Student in Reproductive Health, School of Nursing and Midwifery, Gonabad University of Medical Sciences, Gonabad, Iran.

Abstract

Introduction: Multiple Sclerosis (MS) is known as one of the common progressive chronic diseases in recent decades. Four times increased rate of infected women than men and concurrence between disease and reproductive ages may increase the worries in women. Therefore, this study was performed with aim to investigate the changes in menstrual pattern of infected people before and after diagnosis of MS.
Methods: This correlation and descriptive-analytic study was performed on 132 women with MS referred to MS institute in Khorasan province in 2014-2015. Sampling method was applied based on availability and non-randomized method. Included criteria included single dose therapy, lack of disability and other associated chronic diseases, lack of pregnancy or breastfeeding. To determine the sample size, firstly the variance was calculated based on the primary sample pack of 20 cases, and then using Cochrane simple sampling Formula, sample size was obtained as 132 cases. The study's tools included a structured questionnaire with multiple choice and short answers based on the studies, books and articles regarding to the aim of the study. Content validity was used for questionnaire validity and Cronbach's alpha was used for reliability. Cronbach's alpha was obtained as 0.8. Data was analyzed by software SPSS (version 16). PResults: Single sample Wilcoxon test was used to evaluate the changes in the studied variables before and after infection to the disease based on patients' report and completed questionnaire. Also, t-test and Spearmen test showed no significant differences between duration of infection to the disease, duration of menstruation, menstrual bleeding, menstruation interval and dysmenorrhea (P>0.05).
Conclusion: The results of this study showed that Multiple Sclerosis in infected women who used single drug to control their disease has no effect on menstrual changes such as menstrual bleeding, duration of menstrual bleeding, menstruation interval and dysmenorrhea.

Keywords

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 19, Issue 38
January 2017
Pages 42-47

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