Pathophysiology of vaginal discharge from Iranian Traditional Medicine (ITM) point of view compared with common medicine

Document Type : Review Article

Authors

1 Resident of Traditional Medicine, Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Assistant Professor, Department of Traditional Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Assistant Professor, Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Researcher, Department of Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Abstract

Introduction: Vaginal discharge is one of the most common complaints in women which is associated with failure to treatment and recurrence in many cases. Multiple previous studies have investigated its treatment in the view of complementary medicine, but its etiology has been fewer considered. Therefore, this study was performed with aim to investigate the pathophysiology of vaginal discharge in the view of ITM and compare it with common medicine.
Methods: In this review study, the causes and semiology of "Sayalan-e Rahem" was collected and categorized from ITM manuscripts such as Bouali Sina Qanoun, Aghili Moalejat, Exir Azam, Teb Akbari, …. Also, pathophysiology of leucorrhea was collected from gynecological textbooks such as Novak and Danforth and databases. Then the findings from two perspectives were compared with each other. The common and differentiations were categorized and two viewpoints were explained.
Results: Based on the ITM's view, any discharge from the vagina is called "Sayalan" which could be normal or abnormal. Abnormal sayalan was considered as "Sayalan-e Rahem". The causes of Sayalan-e Rahem is divided into two groups of uterine and extra uterine. Uterine causes include the weakness of "qowwat-ol-ghadhiyah" of the uterine and extra uterine causes include "imtila of any humors" and loos them from the uterus and vaginal discharge. Based on common medicine, leucorrhea can be physiologic and pathologic. Pathologic leucorrhea is known as vaginitis and is divided based on the types of organism that causes infection.
Conclusion: Sayalan in ITM equivalents as leucorrhea in common medicine. Normal Sayalan is also equivalent to physiologic leucorrhea. The causes of pathologic include only infectious factors, while the causes of Sayalan-e Rahem are wider and each of them can be underlying factor for infection and they can also explain the lack of response to treatment and recurrence of vaginitis.

Keywords


  1. Soheili F, Alizadeh S, Hassani M, Bastami P. The pathologic assessment of breast masses, before and after menopause. Iran Obstet Gynecol Infertil 2013; 16(68):21-7. (Persian).
  2. Karimi A, Moradi Z, Sayehmiri K, Delpisheh A, Sayehmiri F. Investigation of 1 to 10-year survival of breast cancer in Iranian women: a systematic review and meta-analysis. Iran Obstet Gynecol Infertil 2016; 19(22):17-25. (Persian).
  3. Adjogatse D, Thanopoulou E, Okines A, Thillai K, Tasker F, Johnston SR, et al. Febrile neutropaenia and chemotherapy discontinuation in women aged 70 years or older receiving adjuvant chemotherapy for early breast cancer. Clin Oncol 2014; 26(11):692-6.
  4. Jensen JD, Cold S, Nielsen MH, Jylling AM, Søe KL, Larsen LB, et al. Trends in breast cancer in the elderly in Denmark, 1980-2012. Acta Oncol 2016; 55(Suppl 1):59-64.
  5. Extermann M, Balducci L, Lyman GH. What threshold for adjuvant therapy in older breast cancer patients? J Clin Oncol 2000; 18(8):1709-17.
  6. Litvak DA, Arora R. Treatment of elderly breast cancer patients in a community hospital setting. Arch Surg 2006; 141(10):985-90.
  7. de Glas NA, Kiderlen M, de Craen AJ, Hamaker ME, Portielje JE, van de Velde CJ, et al. Assessing treatment effects in older breast cancer patients: systematic review of observational research methods. Cancer Treat Rev 2015; 41(3):254-61.
  8. Benevento R, Santoriello A, Gambardella A, Mocerino C, Perna G, Gambardella C, et al. The role of sentinel node biopsy (SNB) in elderly breast cancer patients. BMC Geriat 2010; 10(1):A3.
  9. Valassiadou K, Morgan DA, Robertson JF, Pinder SE, Cheung KL. Successful management of elderly breast cancer patients treated without radiotherapy. World J Surg Oncol 2007; 5:62.
  10. Li JJ, Yu KD, Di GH, Shao ZM. Clinicopathological features and treatment sensitivity of elderly Chinese breast cancer patients. Oncol Lett 2010; 1(6):1037-43.
  11. Rocco N, Iannone L, Rispoli C, De Vito D, Accurso A. Early breast cancer in elderly women: surgery or primary endocrine therapy? BMC Geriat 2010; 10(1):A31.
  12. Malik MK, Tartter PI, Belfer R. Undertreated breast cancer in the elderly. J Cancer Epidemiol 2013; 2013:893104.
  13. Dimitrakopoulos F, Kottorou A, Antonacopoulou AG, Makatsoris T, Kalofonos HP. Early-stage breast cancer in the elderly: confronting an old clinical problem. J Breast Cancer 2015; 18(3):207-17.
  14. Mousavi SM, Montazeri A, Mohagheghi MA, Jarrahi AM, Harirchi I, Najafi M, et al. Breast cancer in Iran: an epidemiological review. Breast J 2007; 13(4):383-91.
  15. Villari SA, Famà F, Scarfò P, Pollicino A, Florio MG. Tailored surgery in elderly patients with breast cancer: our experience. BMC Geriat 2010; 10(Suppl 1):A38.
  16. Wang H, Singh AP, Luce SA, Go AR. Breast cancer treatment practices in elderly women in a community hospital. Int J Breast Cancer 2011; 2011:467906.

Angarita FA, Chesney T, Elser C, Mulligan AM, McCready DR, Escallon J. Treatment patterns of elderly breast cancer patients at two Canadian cancer centers. Eur J Surg Oncol 2015; 41(5):625-34.