The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

Colonization rate of Streptococcus Agalactiae in pregnant women in Iran: A systematic review

Document Type : Review Article

Authors
Arshid Yousefi Avarvand 1
Farzad Khademi 1
Kiarash Ghazvini 2
Mahboube Nakhzari Moghadam 1
Zahra Meshkat 2
1 PhD student in Medical Bacteriology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Associate Professor, Department of Medical Virology, Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
10.22038/ijogi.2017.8446
Abstract
Introduction: Streptococcus agalactiae can be colonized in rectovaginal of pregnant women and subsequently with transmission to infant's results in serious early neonatal diseases such as sepsis and pneumonia. To prevent these complications, antibiotic prophylaxis in pregnant women carrying the bacteria should be performed. There are various statistics about the colonization rate of these bacteria in Iran and the total prevalence is unclear. This review study was performed with aim to evaluate the bacterial colonization in Iran.
Methods: In this review study, colonization rate of Streptococcus agalactiae in pregnant women in Iran was evaluated by search in databases of Google Scholar, Scopus, PubMed, Iran Medex, ISC, ISI Web of Knowledge and MedLib by using the keywords of Streptococcus agalactiae colonization, group B streptococcus colonization, neonatal infection, pregnant women and Iran without time limitation. 32 articles were included in the study based on the rectovaginal colonization rate of pregnant women by Streptococcus agalactiae in different areas of Iran. Data analysis was performed using SPSS software (version 16).
Results: A total of 10548 pregnant women in 17 cities at 32 studies were investigated. Among them, 1568 were colonized with bacteria. The total prevalence rate was estimated 15.5%; the highest and lowest prevalence of Streptococcus agalactiae was observed in Sanandaj (75%) and Kashan (7.6%), respectively.
Conclusion: Screening of Streptococcus agalactiae in all pregnant women at 35-37 weeks of pregnancy and providing epidemiological data to the health care system for preventive measures such as the development of vaccines based on common serotype would be useful. Also, the relationship between Streptococcus colonization and maternal and neonatal complications be evaluated in clinical studies.
Keywords
Iran
Pregnant Women
Streptococcus agalactiae
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 19, Issue 40
March 2017
Pages 45-54