The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

Association between endometriosis and pregnancy hypertension disorders in nulliparous women

Document Type : Original Article

Authors
Farahnaz Mardanian 1
Maryam Kianpour 2
Elaheh Sharifian 3
1 Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
2 Instructor of Nursing and Midwifery, Women's Health Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
3 Resident of Ophthalmology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
10.22038/ijogi.2016.6967
Abstract
Introduction: Endometriosis is one of the common diseases of reproductive age and preeclampsia is a systemic disease with different organs involvement that has much risk for mother especially in HELLP syndrome and eclampsia and for fetus. There are controversy reports about association between endometriosis and pregnancy hypertension disorders. Therefore, regarding to the common background of angiogenesis activity in two disorders of endometriosis and preeclampsia, this study was performed with aim to determine the frequency of preeclampsia and pregnancy hypertension disorders in nulliparous women with endometriosis and the healthy women.
Methods: In this historical cohort study, the files of 893 infertile women who had referred to Alzahra and Beheshti hospitals and Fertility and Infertility center of Isfahan and had undergone laparoscopy due to infertility during 1993-1997 were extracted. 101 women were assigned in each group and preeclampsia and pregnancy hypertension disorders were compared between two groups after laparoscopy. Data were analyzed using SPSS software (version 16), and Fisher Exact, t-test, and Chi-square tests. PResults: There was no significant association between endometriosisand preeclampsia and pregnancy hypertension disorders (P=0.5). 2 women (2%) with endometriosis and 3 (3%) without endometriosis had preeclampsia. Frequency of pregnancy hypertension in women with endometriosis was 6.9% and in women without endometriosis was 8.9% and the difference was not significant (P=0.3).
Conclusion: Frequency of endometriosis and pregnancy hypertension disorders was not different in women with endometriosis and women without endometriosis and the history of endometriosis is not associated with pregnancy hypertension disorders.
Keywords
Endometriosis
Epidemiology
Preeclampsia
Pregnancy hypertension
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 19, Issue 7
May 2016
Pages 1-8