The Effect of Topical Product Containing Sanguisorba Minor Extract on Episiotomy Wound Healing in Primiparous Women: A Triple-Blind Clinical Trial

Document Type : Original Article

Authors

1 M.Sc. Student of Midwifery, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Assistant Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Assistant Professor, Department of Biostatistics, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Professor, Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

10.22038/ijogi.2025.90006.6509

Abstract

Introduction: One of the medical interventions in childbirth is episiotomy which is used to widen the pelvic outlet. The pain resulting from episiotomy affects mother's quality of life. Foxberry plant, with its compounds such as linoleic acid, linolenic acid, flavonoids, tannins, and high levels of beta-carotene, vitamins E and C, and other antioxidants, has anti-inflammatory, anti-congestive, analgesic, and antibacterial potential effects that can be effective in the wound healing process. The present study was conducted with aim to evaluate the effect of topical product containing Sanguisorba minor extract on episiotomy wound healing in primiparous women.
Methods: This randomized triple-blind controlled clinical trial was conducted in 2024 on 86 primiparous women referred to Mahdieh Hospital in Tehran. After delivery, 2 gr of ointment containing Sanguisorba minor was prescribed for topical application on the episiotomy incision twice a day for 10 nights for both groups. Data collection tools included demographic and obstetric information questionnaire, visual pain scale, Rida checklist, and questionnaire to assess complications and satisfaction with the intervention. Data analysis was performed using SPSS software (version 26) and chi-square, independent t-test, Bonferroni, and Mann-Whitney U tests. P<0.05 was considered significant.
Results: There was no statistically significant difference between the Sanguisorba minor and placebo groups in terms of demographic and obstetric characteristics before the intervention (P˃0.05). There was no statistically significant difference in the wound healing score in the two groups before the intervention (P=0.648). The mean wound healing score in the Sanguisorba minor group on the fifth and tenth days was significantly different compared to the placebo group (P˂0.001).
Conclusion: Ointment containing Sanguisorba minor extract reduces pain and improves episiotomy wounds in primiparous women.

Keywords

Main Subjects

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 28, Issue 10
December 2025
Pages 49-61

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