The effects of Nigella sativa, menstrogel, and mefenamic acid on postpartum pain: a randomized clinical trial

Document Type : Original Article

Authors

1 M.Sc. in Midwifery, School of Nursing and Midwifery, Birjand University of Medical Sciences, Birjand, Iran.

2 M.Sc. in Midwifery, Social Determinants of Health Research Center, School of Health, Birjand University of Medical Sciences, Birjand, Iran.

3 Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.

4 Assistant professor, Department of Epidemiology and Statistics, Social Determinants of Health Research Center, School of Health, Birjand University of Medical Sciences, Birjand, Iran.

10.22038/ijogi.2024.82966.6220

Abstract

Introduction: Postpartum pain or uterine contractions is one of the common problems of the postpartum period, which has a significant impact on the quality of life of mothers. Considering the side effects caused by the use of chemical drugs, as well as mothers' anxiety and worry about the medicinal effects of drugs for themselves and their babies, today mothers' desire to use complementary medicine to relieve postpartum pain has increased. The present study was conducted with aim to compare the effect of Nigella sativa vs. menstrogel and mefenamic acid on postpartum pain.
Methods: This triple-blind clinical trial study was conducted in 2021-2022 on 60 multiparous women referring to Walie Asr maternity hospital in Birjand city who gave birth naturally and complained of postpartum pain. The women were randomly assigned to three groups of Nigella sativa, menstrogel, and mefenamic acid capsules and they took capsules every 6 hours for 24 hours. Pain intensity was measured before each dose and one hour later. Data were analyzed by SPSS software (version 22) and ANOVA, chi-square, paired t-test, post hoc Benferroni tests. P<0.05 was considered significant.
Results: The mean score of pain intensity before and after the intervention in the first round did not differ significantly in the three groups (p>0.05), while the results of the analysis of variance showed that the pain intensity has a significant difference in the three groups in the second round after the intervention (p=0.02), the third round after the intervention (p=0.002) and the fourth round after the intervention (p<0.05), and the intensity of pain was less in the Nigella sativa and menstrogel group than the mefenamic acid group, and the consumption of additional painkillers was also lower.
Conclusion: Nigella sativa and menstrogel can be used as an effective herbal medicine to reduce the intensity of postpartum pain.

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Main Subjects

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 11
January 2025
Pages 51-61

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