The complications caused by chorionic villus sampling and amniocentesis in mothers referred to perinatology clinic

Document Type : Original Article

Authors

1 General Practitioner, Student Research Committee, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

2 Midwifery Expert, Vice President of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

3 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

4 Assistant Professor, Department of Community Medicine, Iran Aging Research Center, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

5 M.Sc.of Midwifery, Vice President of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

6 Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

10.22038/ijogi.2024.75465.5884

Abstract

Introduction: After screening tests, CVS and amniotic fluid sampling (amniocentesis) are two definitive methods for prenatal diagnosis of chromosomal abnormalities and genetic diseases. The present study was conducted with aim to evaluate the complications caused by chorionic villus sampling and amniocentesis in mothers referred to perinatology clinic of Sabzevar University of Medical Sciences.
Methods: This analytic cross- sectional study was performed during 2016–2018. A total number of 448 pregnant mothers were included in the study, 397 of whom underwent amniocentesis and 51 underwent CVS. Two weeks after the procedures, five complications, including PPROM, IUFD, infection, spotting and spontaneous abortion were assessed. Data analysis was performed using SPSS statistical software (version 24) and t-test and chi-square test. P<0.05 was considered significant.
Results: In amniocentesis, spontaneous abortion occurred in 0.251%, amniotic leakage 0.755%, spotting 0.502%, chorioamnionitis 0.251% within 14 days after the procedure. There was no fetal intrauterine death in this method. In CVS, there were not any complications. There was no significant difference between the two methods in terms of side effects (p=0.98).
Conclusion: Considering the complications, CVS and amniocentesis are low risk methods for prenatal diagnosis.

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Main Subjects

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 10
December 2024
Pages 29-36

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