Prevalence of overweight and obesity and its relationship with chemical pregnancy in infertile women after assistant reproductive therapy

Document Type : Original Article


1 Ph.D Student, Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, ACECR, Royan Institute, Tehran, Iran.

2 Assistant Professor, Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, ACECR, Royan Institute, Tehran, Iran.


Introduction: Obesity and overweight is one of the most important health-related problems worldwide. Obesity can affect chemical pregnancy success rate after assistant reproductive therapy. This study was performed with aim to determine the association between body mass index (BMI) and chemical pregnancy after IVF or intracytoplasmic sperm injection for infertile women in Royan Institute.
Methods: In this retrospective cohort study, 2983 infertile women who referred to Royan Institute from 2012 to 2014 were evaluated. The independent variable was body mass index and the outcome was the occurrence of chemical pregnancy in infertile women which were determined using β-HCG levels. Data analysis was performed using Stata software (version 13). PResults: The mean of BMI in infertile women was 26.7±4.31 kg/m2 and the prevalence of overweight and obesity in infertile women was 56.99%. The chance of non-success in chemical pregnancy in women with class II obesity was 2.69 times against women with normal BMI and the chance of non-success in chemical pregnancy in overweight women was 1.28 times against women with normal BMI.
Conclusion: There is a significant relationship between body mass index and rate of chemical pregnancy and the chance of success in chemical pregnancy in overweight and obese women is less than women with normal BMI.


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