A rare case of vulvar metastatic tumor with renal origin

Document Type : Case report

Authors

1 Associate Professor, Department of Obstetrics and Gynecology, Gynecologic Oncology Fellowship, Women's Health Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Resident, Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Fellowship Resident of Gynecologic Oncology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction: Vulvar cancer, primary or metastatic, is a rare tumor constituting <1% of all female cancers. Primary vulvar cancers are responsible for 3–5% of genital tumors, while metastatic vulvar cancers have lower rate and include 5–8% of vulvar cancers. The entire female genital system is at risk for metastases from intragenital and extragenital organs. Among genital organs, vulva has the least rate of metastasis. Origin of metastases in 46.9% is from other genital organs and in 53.1% is non-genital. In non-genital cases, gastrointestinal adenocarcinoma is more common than all. Metastasis from extragenital remote sites such as kidney, stomach, gestational choriocarcinoma, malignant melanoma and neuroblastoma to the vulva has been reported. Metastasis with urothelial origin has lower rate that in this study, a case of metastasis from kidney to vulva is reported.
Case report: A 56 years old woman with history of renal cell carcinoma with ulcerative vulvar mass referred. Biopsy of vulva reported metastasis of renal cell carcinoma. Patient underwent local resection of lesion and chemotherapy.
Conclusion: The high clinical suspicion for vulvar metastasis should be considered in women with history of cancer who refer with vulvar lesion. Early diagnosis and appropriate treatment can affect the prognosis of these patients.

Keywords

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 19, Issue 17
July 2016
Pages 24-29

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