Demographic survey of 600 patients with gynecologic cancers in Mashhad, Iran in 1985-2012

Document Type : Original Article

Authors

1 Resident of Community Medicine, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Assistant Professor, Department of Obstetrics and Gynecology, Ghaem Hospital, Women's Health Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 General Physician, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 General Physician, Students Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 Assistant Professor, Department of Community Medicine, Cancer Research Center, Omid Hospital, Patient Safety Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Introduction: Lack of accurate, adequate and reliable information about malignancies of the female reproductive system in our country is sensible, this study was performed with aim to evaluate demographic characteristics of 600 patients with gynecologic cancers referred to Mashhad Oncology clinic in order to determine the relative frequency and mean age in different gynecologic cancers in Iran over the past three decades
Methods: This descriptive, analytic, and cross-sectional study was performed with aim to evaluate the patients with gynecologic cancers referred to Mashhad Oncology-Radiotherapy clinic. Epidemiologic data were obtained from records of the patients referred to private oncology center from 1985 to 2012 by using checklist. The study's time was divided into three intervals: 1985-1994, 1995-2004 and 2005-2012. Data analysis was conducted by the SPSS software (version 11.5), and Chi-square, Kolmogrov-Smirnov, Kruskal-Wallis, and ANOVA. PResults: A total of 579 cases were analyzed. Overall, the most frequent cancers was cervical cancer (43.5%), The relative frequency of gynecological cancers had significant differences among three intervals (P<0.001). Cervical cancer was the most frequent cancer in the first and second time periods, but uterine cancer had the highest relative frequency during the third interval. The mean age of patients at diagnosis was 48.63± 14.6 years that had significant differences among cancer types (P<0.001). The highest (56.1±10.7) and lowest (28.5±11.0) means of age were related to vagina cancer and trophoblastic cancer, respectively. Increased mean age at diagnosis for uterine cancer (P=0.026) and ovarian cancer (P=0.003) was statistically significant.
Conclusion: Cervical cancer was the most frequent cancer in our patients. The highest mean age was related to cervical cancer and lowest one was related to trophoblastic cancer. The mean age at diagnosis had ascending trend during three decades.

Keywords

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 19, Issue 3
April 2016
Pages 1-8

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