Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome
Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrinal disorders in women at reproductive age. In many cases, PCOS is associated with infertility and increased risk of metabolic syndrome. This study was performed with aim to investigate the effect of 8-week resistance exercise and calcium supplementation on anti-mullerian hormone (AMH) level and metabolic parameters in women with PCOS. Methods: This semi-experimental study was performed with pretest–posttest design on 30 women with PCOS who were referred to one of the medical centers of Arak in 2014. They were randomly assigned to three groups of resistance exercise and placebo, resistance exercise and calcium supplementation consumption (1000 mg/d), and control with 10 cases in each group. The protocol consisted of 3 sessions per week of exercise for 8 weeks, each session including 1-2 sets of 5–20 repetitions at 40–60% of 1RM(one repetition maximum). Serum levels of AMH and metabolic parameters were assessed before and after the training period. Data were analyzed using SPSS software (version 18), and two-way ANOVA and ANCOVA tests. PResults: After 8 week total cholesterol resistance exercise, LDL-c, triglycerides and insulin resistance index were significantly decreased (P<0.05). Data analysis showed that calcium supplementation in conjunction with resistance exercise leads to more improvement in metabolic indices and serum level of AMH (P<0.05). Conclusion: Resistance training in conjunction with calcium supplementation for two months can have beneficial effects on metabolic indices and ovarian reserve in women with PCOS.
Vural B, Caliskan E, Turkoz E, Kilic T, Demirci A. Evaluation of metabolic syndrome frequency and premature carotid atherosclerosis in young women with polycystic ovary syndrome. Hum Reprod 2005; 20(9):2409–13.
Gambineri A, Pelusi C, Manicardi E. Glucose intolerance in a large cohort of mediterranean women with polycystic ovary syndrome: phenotype and associated factors. Diabetes 2004; 53(9):2353–8.
Cascella T, Palomba S, De Sio I, Manquso F, Giallauria F, De Simone B, et al. Visceral fat is associated with cardiovascular risk in women with polycystic ovary syndrome. Hum Reprod 2008; 23(1):153-9.
Larzadeh N, Ghasem Nejad A, Mohammad Pour J. Effect of metformin on outcome of intrauterine insemination (IUI) in insulin infertile women with polycystic ovarian syndrome. Iran J Obstet Gynecol Infertil 2014; 17(128):1-11. (Persian).
Moran L, Norman RJ. Understanding and managing disturbances in insulin metabolism and body weight in women with polycystic ovary syndrome. Best Pract Res Clin Obstet Gynaecol 2004; 18(5):719–36.
Harrison CL, Stepto NK, Hutchison SK, Teede HJ. The impact of intensified exercise training on insulin resistance and fitness in overweight and obese women with and without polycystic ovary syndrome. Clin Endocrinol 2012; 76(3):351-7.
Shi H, Dirienzo D, Zemel MB.Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2-agouti transgenic mice. FASEB J 2001; 15(2):291-3.
Tehrani HG, Mostajeran F, Shahsavari S. The effect of calcium and vitamin D supplementation on menstrual cycle, body mass index and hyperandrogenism state of women with poly cystic ovarian syndrome. J Res Med Sci 2014; 19(9):875-80.
Hossein Rashidi B, Haghollahi F, Tehranian N, Shariat M, Zayeri F, Bagheri M, et al. Therapeutic effects of vitamin D and calcium in patients with polycystic ovary syndrome. J Reprod Infertil 2006; 7(3):225-33
Saremi, A., & Yaghoubi, M. S. (2016). Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome. The Iranian Journal of Obstetrics, Gynecology and Infertility, 18(180), 7-15. doi: 10.22038/ijogi.2016.6581
MLA
Abbas Saremi; Mohadaseh Sadat Yaghoubi. "Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome", The Iranian Journal of Obstetrics, Gynecology and Infertility, 18, 180, 2016, 7-15. doi: 10.22038/ijogi.2016.6581
HARVARD
Saremi, A., Yaghoubi, M. S. (2016). 'Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome', The Iranian Journal of Obstetrics, Gynecology and Infertility, 18(180), pp. 7-15. doi: 10.22038/ijogi.2016.6581
VANCOUVER
Saremi, A., Yaghoubi, M. S. Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome. The Iranian Journal of Obstetrics, Gynecology and Infertility, 2016; 18(180): 7-15. doi: 10.22038/ijogi.2016.6581