Metastatic Choriocarcinoma in Postmenopausal Woman: A Case report

Document Type : Case report


1 Professor of Obstetrics & Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Resident in Obstetrics & Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Associate Professor of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


Introduction:Gestational trophoblastic neoplasia (GTN) usually occurs during women’s reproductiveages and it is very unusual in postmenopausal women. The aim of this study is to present a case of GTN in a postmenopausal woman.
Case Report: A 60-year-old woman with history of vaginal bleeding and a mass lesion was admitted to Ghaem hospital affiliated to Mashhad university of medical sciences. She afterwards underwent surgical biopsy of vaginal mass and histological evaluation revealed metastatic choriocharcinoma. Investigation for extention of metastases performed and the final diagnosis was a stage IIIc choricaricnoma. Patient received EMA-CO regimen chemotherapy (Etoposide, Methotrexate, Actinomycine, Cyclophosphamide, Vincristin) and after seven courses of chemotherapy she experienced a complete relief.
Conclusion: Physicians should not ignore the possibility of GTN in different ages with a variety of presentations.


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