Prevalence of Vitamin D deficiency and related factors Among Pregnant Women referred to Masjed Soleimam health centers in 2014

Document Type : Original Article


1 PhD student of Reproductive Health, School of Nursing and Midwifery Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Professor, Department of Obstetrics and Gynecology, Reproductive Endocrinology Research Center, Metabolism and Endocrine Sciences Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Associate professor, Department of Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Professor, Department of Endocrine and Metabolism, Obesity Prevention and Treatment Research Center, Metabolism and Endocrine Sciences Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

5 Professor, Department of Biostatistics, School of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran


Introduction:Vitamin D deficiency in pregnancy is widespread in many parts of the world, and there is an association between vitamin D level and adverse outcomes of pregnancy. Considering the importance of maternal health progress, this study was performed with aim to determine the prevalence of vitamin D deficiency in first trimester of pregnancy and evaluation of related factors affecting this vitamin.
Methods: This cross-sectional study was performed on 1581 pregnant women during their first prenatal visit in Masjed-Soleiman health centers in 2014. Maternal data was collected using a questionnaire. A blood sample was taken from each woman to measure serum 25-hydroxy vitamin D using ELISA method by Immunodiagnostic Systemdimided (IDS) kit. Was analyzed by SPSS software (version 18), and descriptive and analytical tests (Spearman, variance analysis, independent t). P<0.05 was consider significant.
Results: Mean serum level of 25(OH)D was 13.05 ng/ml(SD± 6.36) and overall prevalence of vitamin D deficiency estimated as 84%. Mean serum level of was significantly associated with duration of sun exposure, use of sunscreens, type of Hejab and type of dwelling (P<0.0001). But, there was no correlation between mean level of vitamin D and maternal age (P=0.773), gestational age (P=0.174), parity (P=0.509), and occupation (P=0.786).
Conclusion: Considering high prevalence of vitamin D deficiency among pregnant women in Masjed-Soleiman, it seems that screening and vitamin D supplementation be essential in this population.


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