Prevalence of Gestational Diabetes Mellitus in Iran: A Systematic Review and Meta-Analysis Study

Document Type : Original Article

Authors

1 M.Sc. Student of Biochemistry, Student Research Committee, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

2 Assistant professor, Department of Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

3 B.Sc. Student of Laboratory Sciences, Student Research Committee, Faculty of Para medicine, Ilam University of Medical Sciences, Ilam, Iran.

4 Assistant professor, Department of Biostatistics, Psychosocial Injuries Research Center, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran. Assistant professor, Department of Social Medicine, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Abstract

Introduction: Gestational diabetes mellitus is one of the main maternal problems during pregnancy that can make many complications for mother and fetus. Various studies have reported different prevalence of this problem. Since little studies have been done to estimate the total prevalence of gestational diabetes in Iran; we performed a systematic review and meta-analysis study to estimate the prevalence of gestational diabetes in Iran.
Methods: This study is a systematic review and meta-analysis of gestational diabetes in Iran. By searching the SID, Magiran, Irandoc, Medlib, Google, PubMed and ISI-Web of Science databases, 21 published articles between 1992 and 2008 were found which performed in Iran. Results of the studies were combined using random-effects model for meta-analysis. Heterogeneity among studies was assessed using the I2 index. To investigate the relationship between prevalence of gestational diabetes mellitus and years of study and sample size meta-regression was used. Data were analyzed using STATA software version 11.2. P value less than 0.05 was considered significant.
Results: In 21 studied articles, the prevalence of gestational diabetes estimated 4.9% (CI%95:3.9-5.8). The lowest and highest prevalence of gestational diabetes were 0.7% in the province of Kermanshah and 18.6% in the province of Karaj.
Conclusion:Due to the differences in prevalence of GDM in Iran, It is proposed for identifying reasons for these differences, Research takes place in a provincial screening. With proper planning and health policies, the rising prevalence of the disease and its complications could be prevented.
 

Keywords