Prevalence of Malignant Adnexal Masses in pregnancy at Gynecology and Oncology Department of Ghaem Hospital from 2010 to 2014

Document Type : Original Article

Authors

1 Professor, Department of Obstetrics and Gynecology, Women's Health Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Associate Professor, Department of Obstetrics and Gynecology, Women's Health Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Fellowship of Gynecologist Oncologist, Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

5 Resident of Fellowship of Gynecologist Oncologist, Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

6 Resident of Obstetrics Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction: The majority of adnexal tumors in pregnancy are benign. It is important to distinguish between benign and malignant ovarian tumors. Due to the sensitivity of pregnancy, especially malignant adnexal masses in pregnancy and the lack of accurate information from the prevalence of this malignancy, this study was performed with aim to evaluate the prevalence of adnexal masses in pregnancy.
Method: This cohort study was performed on 53 pregnant women with adnexal mass who needed to surgery referred to gynecology oncology department of Mashhad Ghaem Hospital during 2010-2014. Evaluating variables included maternal age, gestational age, sonographic characteristics of tumor, clinical symptoms of patient, type of surgery, pathology status of tumor, performed chemotherapy and prognosis of mother and fetus. Data collection tool was a questionnaire. Data was analyzed by SPSS statistical software (version 16), and Mann-Whitney and Kruskal-Wallis tests. PResults: the prevalence of malignancy was 21% (11patients). The most frequent malignancy in adnexal masses and pregnancy was germ cell tumors. 55% of these tumors were in stage 3 and 4. Borderline tumors included 18% of malignant tumors. In this study, maternal mortality rate of 5.6% and maternal mortality rate of 3.8% was reported. 
Conclusion: Adnexal masses in pregnancy should be evaluated with more care and sensitivity and in cases of suspected or stable tumors, it is better to perform surgery in gynecologic oncology centers.

Keywords

References

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