Relationship between Fat Mass (FM) and Lean Body Mass (LBM) with Femur Neck Bone Mineral Density (BMD) in Active and Non-active Postmenopausal Women

Document Type : Original Article

Authors

1 Assistant professor, Department of Exercise Sciences, Kashmar Excellent Training Center, Kashmar, Iran

2 M.Sc. of Physical Education, School of Physical Education, Mashhad Azad University, Mashhad, Iran.

3 M.Sc. of Statistics, Faculty of Medicine, School of Medicine, Khorasan Shomali University of Medical Sciences, Bojnord, Iran.

Abstract

Introduction: Researches have shown that body weight composed fat mass (FM) and lean body mass (LBM) is related with bone mineral density (BMD). This study was performed with the aim to determine the relationship between FM and LBM with BMD of femur neck in active and non-active postmenopausal women.
Methods: This correlation descriptive study was performed on 12 active and 12 non-active postmenopausal women in 2011. FM and LBM and BMD of femur neck of the subjects were measured by DEXA. Collected data were analyzed by SPSS software (version 16) and Smironov-Kolmogrov test, Pearson correlation test, and multiple regression. P ≤ 0.05 was considered significant.
Results: There was significant relationship between FM with BMD of femur neck in non-active postmenopausal women group (r = 0.713, P = 0.009). Also, there was significant relationship between FM and LBM with BMD of femur neck in active postmenopausal women (r=0. 624, P=0.03 and r =0.793, P=0.002). 
Conclusions: In active postmenopausal women, LBM can be considered as strong predicting of BMD of femur neck, but FM is just as determinant factor of BMD of femur neck in non-active postmenopausal women.

Keywords

References

  1. Abolhassani. F, Mohammadi. M., Sultan. A, disease burden of osteoporosis in Iran in year 2001. Tehran University of Medical Sciences, medical Journal of Reproduction and infertility, 2004, (1) :25-36.(Persian ).
  2. Taghizadeh.Z, Zolfaghari.M, Mortaz Hejri.S, Maghboli.G, Kazemnezhad.A, Pazhohi.M, investigating the air pollution with bone density mearurements and bone biochemistry indicators in various residents of Tehran. University of Medical Sciences, Journal of Reproduction and infertility, Winter (2004): (1) :43-52.(Persian ).
  3. David A, Greene A, Gevaldine A , Naughton M.“Adaptive skeletal responses to mechanical loading during adolescence”. Sports medicine,.(2006),36:723-732.
  4. Slemenda CW , Miller JZ , Hui SL, Reister k , Johnston CC. Role of physical activity in the development of skeletal mass in children.JBone Miner Res.1991;6(11);1227-1233.
  5. Shabani M. Bone mineral density of upper and lower limbs in elite cyclists. Sport Physiology: Research on Sport Science, Spring 2010, 26:133-144.
  6. Puntila E, Kroger H, Lakka T et al. leisure-time physical activity and rate of bone loss among peri and post menopansal women: alongitudinal study. Bone 2001; 29(5): 442-446.
  7. Gusin N, Raimundo A, leal A. Low-frequency vibratory exercise reduces the risk of bone fracture more than walking: a randomized controlled trial. BMC Musculoskeletal Disord. 2006 Nov; 30; 7:92
  8. Felson DT, Zhang Y , Hannan MT , Andersson JJ. Effect of weight and body mass insex on bone mineral density in men and women ; the framinghan study. J mine Res 1993; 8 ;57-73.
  9. Langdon A.Phyloquinone (vitamin K1) intakes and serum under carboxylated osteocalsin levels in Irish Postmenopausal women.British Journal of Nutrition.2006,95(5):982-988.
  10. Gaeini.A, Dabydy Roshan.V, principles of sports physiology exams and special topics sports , Tehran 2006 Volume 2, pp. 88-119.(Persian ).
  11. Reid IR , Ames R, Evance MC, et al. Determinants of total body and regional bone mineral density in normal postmenopausal women –a key role for fat mass.J Clin Endocrinol Metab. 1992; 75;45-51.
  12. Reid I Relationships among body mass, its components , and bone. Bone 2002; 31; 547-55.
  13. Nakaoka D, Kaji H , et al.Determinants of bone mineral density and spinal fracture risk in postmenopausal Japanese women.Osteoporosis Int,2007,12(7) :548-554.
  14. Douche T, Mastsuo T,Uto U, kuwahatu T,oki T, Nagata Y. FFM body mass and bone mineral density in physically exercising postmenopausal women.Matuvitas, 2003,45:185-190.
  15. 15. Nur H, Toraman NF, Arica Z, Sarier N, Samur A. The relationship between body composition and bone mineral density in postmenopausal Turkish women. Arch Gerontol Geriatr. 2012 ;54(3):e315-21.
  16. Harris S, Dallal GE, Dawson –Hughesb. Influence of body weight on vate of changes in bone density of the spine, hip and radius of post-menopausal women. Calcify-tissne into 1992,50:19-35.
  17. Beck TJ ,Oreskovic TL , Stone KL , et al.Strutual adaptation to changing skeletal load in the progression toward hip fragility : the study of osteo porotic fractures.j Bone Miner , 2001; 16 :1108-1119
  18. Nguyen TV, Kelly PJ, Sambrook PN, et al. Lifestyle factors and bone density in the elderly; implications for osteoporosis prevention. J Bone Miner Res 1994:9:1339-46
  19. Edelstein SL , Barett –connor E. Relation between body size and bone mineral density in elderly men and women. Am J Epidemiol ,1993:138 (3);160-169.
  20. Egil E , Johan G.B , Grethe S,Tell Clara G , Gjesdal J.I , Halse G. Impact of FFM mass and fat mass on bone mineral density : The Horland Health study.Maturitas , Volume 59, issue 2, 20 Februay 2008: pages 191-200.
  21. Binbridge K. E, Sowers M, Risk Factors for low bone mineral density and the 6- year rate bore loss among premenopausal woman, Osteoporos Int, (Epub ahead of print) , 2004.
  22. Barrera G,Bunout D,Gattas V, Maria Pia de la Maza, Leiva L,Hirsch S.A.high body mass index protects against femoral neck osteoporosis in healthy subject. Nutrition; 2004; 20(9): 769-771.
  23. Karlson MK, Physical activity, skeletal health and fractures in a long term perspective. Journal of Musculoskeletal Neuron interact. 2003;4(1): 12-21.
  24. Montgomery E, Pennington C, Isales CM et al. Muscle - bone interaction in dystrophin –deficient and myostatin – deficient mice. Anat Rec A Discov Mol Cell Evol Biol. 2005 Sep; 286(1): 814-22.
  25. Shabani M.Bone mineral density in elite cyclists.PHD thesis in university of picardie Jules Verne in French , December 2007.
  26. 26. Wang MC, Bachrach LK , Van-Loan M, et al. The relative contributions of FFM tissue mass and fat mass to bone density in young women.Bone 2005; 37; 474-81.
  27. Salamone LM, Glynn N ,Black D, et al.Body composition and bone mineral densityin prrimenopausal women. J bone miner res,1995;10;1762-1768.
  28. Lenchik L , Register TC, Hsu FC, Lohman K, Nicklas BJ, Freedman BJ.Adiponectin as a novel determinant of bone mineral density and visceral fat.Bone 2003;33;646-51.
  29. 29. Pasco JA , Henry MJ , Kotowicz MA , Collier GR , Ball MJ ,Ugoni AM , et al.Serum leptin levels are associated with bone mass in nonobese women. J Clin Endocrinol Metab 2001: 86:1884-7.
  30. Thomas T. Leptin , A potential mediator for protective effects of fat mass on bone tissue. Jt Bone spine 2003;70;18-21.
  31. Kyle UG, Morabia A , Schutz Y , Pichard C ,Sedentarism affects body fat mass index and fat – free mass index in adults aged 18 to 98 years. Nutrition 2004:20:255-60.

Files

Share

How to cite

Statistics