sHot Flashes of Menopause and Herbal Medicine in Iran: A Systematic Review

Document Type : Original Article

Authors

1 PhD Student of Reproductive Health, Department of Reproductive Health, Student Research Committee, Faculty of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran.

2 Assistant Professor, Department of Reproductive Health, Faculty of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran.

Abstract

Introduction: In the area of menopause and it’s related problems, alternative and complementary therapies are expanded to some extent. As such study hasn’t been done till now, here under the title of Hot Flashes of Menopause and Herbal Medicine , it’s aimed to analyze clinical trials of herbal medicine and to summarize them.
Methods: In this study some informations were gathered from database SID, IranMedex, IranDoc, Magiran, Google Scholar, PubMed and journals of herbal medicines also papers from the beginning of the year 2000 to 2013 were evaluated. These papers were evaluated under the scrutiny of  Jadad scale and those were used in the study which got the score 3 or more. Data were analyzed qualitatively.
Results: Among 27 clinical trials which were analyzed, 22 of them got the score 3 or more under the scale of Jadad. In this research, 6 papers were devoted to soybeans, 4 to five-finger herb, 3 to Licorice, 2 to fenugreek, 1 to Linnaeus' flower clock, 1 to valerian, 1 to flaxseed, 1 to paper sage, 1 to geranium tea, 1 to anise, 1 to manee papers, 1 to red clover, 1 to black kohosh and 1 to the plant hypericum. Consequently, due to the heterogeneity of the time that had been spent for studies, doses and specific products; performing a meta-analysis was impossible.
Conclusions: In Iran different papers have been written in this area. Although numerous and perfectly-valid papers exist which focus on soybeans, it is suggested for treatment of menopause problems.

Keywords

References

  1. In: Berek G, Berek DL. Berek & Novak's gynecology. 15thed. Philadelphia:Lippincott Williams and Wilkins;2012:1109-1132.
  2. Abdollahi F, Azadbakht M, Shabankhani B, Rezaee F, Moslemizadeh M. [Effect of the Glycyrriza glabra on complication of menopause] [Article in Persian]. J Mazanaran Univ Med Sci 2005;16(56)75-82.
  3. Fritz MA, Speroff L.Clinical gynecologic Endocrinology and infertility. 8th ed. Philadelphia:Lippincott Williams and Wilkins;2011.
  4. Guttuso T Jr, Kurlan R, McDermott MP, Kieburtz K. Gabapentin's effects on hot flashes in postmenopausal women: a randomized control trial. Obstet Gynecol 2003 Feb;10(2):337-45.
  5. Elkind-Hirsch K. Cooling off hot flashes: uncoupling of the circadian pattern of core body temperature and hot flash frequency in breast cancer survivors. Menopause 2004 Jul-Aug;11(4):369-71.
  6. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996 Feb;17(1):1-12.
  7. Fleming T. PDR for herbal medicines. 2nd ed. Montvale:Medical Economics Company;2000:469-74.
  8. Moyad MA. Complementary/alternative therapies for reducing hot flashes in prostate cancer patients: therapies the existing indirect dates from studies of breast cancer and postmenopausal women. Urology 2002 Apr;59(4 Suppl 1):20-23.
  9. Lobo RA. Treatment of the postmenopausal women: basic and clinical aspests. 2nd ed. Philadelphia:Lippincott Williams & Wilkings;1999.
  10. Prodan M, Tabra V. Research concering the increase of herb of culinary Sage through certain cultivation technologyies in the conditions of the didactic station in Temisoarna in 2007. J Agric Sci 2010;42(1(:35-39.
  11. Bommer S, Klein P, Suter A. First time proof of sage’s tolerability and efficacay in menopausal women with hot flushes. Adv Ther 2011 Jun;28(6):490-500.
  12. Bluemental M, Goldberg A, Brinckmann J. Herbal medicine: expanded commission monographs: the indispensable and affordable scientific herbal reference. Newton:Integrative Medicine Communication;2000.
  13. Mirheidar H. [Botany application of plants in prevention and treatment of diseases]. 4th ed. Tehran:Daftar-e Nashr-e-Farhang Islami;2003. [in Persian].
  14. Jahanara F, Haerizadeh M.[Information and application of official hebal medicine]. Tehran:Darogostar Factory;2003. [in Persian].
  15. Mackey R, Eden J. Phytostrogens and the menopause. Climacteric 1998 Dec;1(4):302-8.
  16. Kim MK, Chung BC, Yu VY, Nam JH, Lee HC, Hon KB, et al. Relationships of urinary phyto-oecstrogen excretion to BMD in postmenopausal women. Clin Endocrinol 2002 Mar;56(3):321-8.
  17. Mahady GB, Parrot J, Lee C, Yun GS, Dan A. Botanical dietary supplement use in peri-and postmenopausal women. Menopause 2003 Jan-Feb;10(1):65-72.
  18. Shifren JL, Schiff I. Menopause. In: Berek JS, Berek DL. Berek & Novak's gynecology. 14th ed. Philadelphia:Lippincott Williams and Wilkins;2007:1323-38.
  19. Lewis JE, Nickell MD, Thompson LU, Szalai JP, Kiss A, Hilditch JR. A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause. Menopause 2006 Jul-Aug;13(4):631-42.
  20. Brooks JD, Ward WE, Lewis JE, Hilditch J, Nickell L, Wong E, et al. Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than doses supplementation with an equal amount of soy. Am J Clin Nutr 2004 Feb;79(2):318-25.
  21. Kazamian A, Bromanfar Kh, Alireza GH, Norian K. [Effect of Vitex and pasibi on hot flash of menopause women] [Article in Persian]. J Shahrekord Univ Med Sci 2006;7(1)39-44.
  22. Bromanfar Kh, Kazamian A, Safdari F, Delaram M, Norian K. [Effect of the Vitex on hot flash of menopause in Isfahan] [Article in Persian]. J Birjand Univ Med Sci 2006;14(3)13-9.
  23. Taghizadeh Z, Rezaee A, Kazemnejad A, Mirsaedi Z. [Effect of vitex on symptom of menopause] [Article in Persian]. Hayat J 2006;12(1)67-76.
  24. Kazamian A, Sereshti M, Frozandeh N, Akbari N. [Effect of passion flower on hat flash of menopause] [Article in Pertion]. J Babol Univ Med Sci 2006;7(4)36-43.
  25. Samiee H, Sina S. [Comperesion of the Soy herb with HRT on symptoms of menopause] [Article in Persian]. J Babol Univ Med Sci 2006;7(4)36-43.
  26. Ebrahimi M, Taghizadeh M. [Effect of Soy protein supplementation on menopausal symptoms] [Article in Persian]. Hakim 2009 Winter;11(4):16-20.
  27. Baghdari N, Akbari A, Ayati S, Emami A, Esmaieli H. [Effect of the Flaxseed on hot flashes in women at climacteric] [Article in Persian]. Iran J Obstet Gynecol Infertil 2011;14(1):37-47.
  28. Nahidi F, Zare E, Mojab F, Alavi Majd H. [The effect of Licorice root extract on hot flashes in menopause] [Article in Persian[. Pejouhandeh 2011;16(1):11-7.
  29. Sadeghi H, Bakshi M, Behbodi Z, Godarzi S, Haghani H. [Effect of sage extract on hot flashes in postmenopausal women] [Article in Persian]. Complement Med 2012;2(4):324-35.
  30. Nahidi F, Taherpour M, Mojab F, Alavi Majd M. [Effect of Anison on hot flash of menopause] [Article in Persian]. Pejouhandeh 2008 Aug-Sep;3(13):167-73.
  31. Shahbazzadegan S. [Effect of shamdani tea on hot flash of menopause] [Article in Persian]. Complement Med 2010;1(1)103-5.
  32. Hakimi S, Mohammadalizadeh S, Delazar A, Abbasalizadeh F, Bamdad Moghaddam R, Siiahi MR, et al. Effect of fenugreek seed on hot flash in menopausal women. J Me Plants 2006;19(5):9-14.
  33. Sekhavat L, Dehghani R, [Effect of the soy protein on hot flash of menopause women in Yazd] [Article in Persian]. ,J Women Midwifery 2012;15(6)10-6.
  34. Abaspor Z, Hagikhani NA, Afshari P. [Effect of vitex agnus castuson menopausal symptoms in postmenopausal women] [Article in Persian]. J Sabzevar Univ Med Sci 2006;12(2)26-30.
  35. Asali Z, Fahami F, Aslani A, Fathizadeh N. [Comparative evaluation of st jhon’s wrot and passion flower effect on hot flash and insomnia in menopausal woman] [Article in Persian]. Complement Med 2013;3(1)30-40.
  36. Taavoni S, Shakeri F, Haghani H, Gooshegir SA. [Effect of red clover on vasomotor symptoms and heart discomfort of menopausal women] [Article in Persian]. Complement Med J 2012;3(1)32-40.
  37. Yari F, Ghafarzadeh M, Tarahi M. [Study of effect of soy supplementation on hot flash in menopause women in Khoramabadan Aligodarz] [Article in Persian]. Yafteh J Lorestan Univ Med Sci 2000;4(5):43-6.
  38. Menati L, Siahpoosh A, Tadayon M. [A randomized double blind clinical trial of licorice on hot flash in postmenopausal women and comparison with hormone replacement therapy] [Article in Persian]. Sci Med J Ahwaz Univ Med Sci 2010;9(65):157-67.
  39. Enjezab B, Mozaffari-Khosravi H, Khoshbin A, Faraj-Khoda T. [Effect of Soybeans on hot flashes in postmenopausal women] [Article in Persian]. J Shahid Sadoughi Univ Med Sci 2009;17(4)242-8.
  40. Saghafi N, Mahmodinya M, Ayati S, Bahdani F, Shakeri MT, Rakhshandeh A. [Comparision of Black kohosh and floxitin on symptom of menopause] [Article in Persian]. Iran J Obstet Gynecol Infertil 2013 Jan;15(32):29.
  41. Ehsanpour S, Salehi K, Zolfaghari B, Bakhtiari S. The effects of red clover on quality of life in post-menopausal women. Iran J Nurs Midwifery Res 2012 Jan;17(1):34-40.
  42. Abdali K, Khajehei M, Tabatabaee HR. Effect of St John’s wort on severity, frequency, and duration of hot flashes in premenopausal, perimenopausal and postmenopausal women: a randomized, double-blind, placebocontrolled study. Menopause 2010 Mar;17(2):326-31.
  43. Akbari Torkestani N, Attarha M, Heidari T, Narenji F. [Effect of the fenugreek and flaxseed on hot menopausal hot flash] [Article in Persian]. Complement Med J 2011;1(1)7:68-74.
  44. Kashani M, Bathaie F, Ogaghi M, Bathaee M, Akhonzadeh Sh. [Herbal medicine on menopause: a systematic review] [Article in Persian]. J Mazanaran Univ Med Sci 2005;16(56)75-82.
  45. Borrelli F, Ernst E. Black cohosh (Cimicifuga racemosa) for menopausal symptoms: a systematic review of its efficacy. Pharmacol Res 2008 Jul;58(1)8-14.

Files

Share

How to cite

Statistics