Effect of Herbaceous Medicines effective in hot flashes of Menopause women: a systematic Review and Meta-Analysis in Iran

Document Type : Original Article


1 B.Sc. Student of Midwifery, Student Research Committee, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.

2 Lecture of Midwifery, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.

3 M.sc of Biochemistry, Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.

4 Assistant Professor, Department of Biostatistics, Prevention of psychosocial impairment Research Center, Ilam University of Medical Sciences, Ilam, Iran.


Introduction: The most common phenomenon of menopause period is hot Flashes. nowadays using herbaceous medicines in hot Flashes treatment has gained much attention. The aim of this study is to investigate the effect of herbaceous medicines in hot Flashes treatment.
Methods: Current study is a systematic and Meta-analysis review. Information about the effect of herbaceous medicines on hot Flashes in menopause period collected from Google scholar, IranMedex, Magiran, MedLib, PubMed, SID, IranDoc databases. 16 articles published between 2000 and 2009 worldwide were selected. Data were analysed by STATA software (version12.2) using Meta-analysis method (random selection model).
Results: of 16 articles, 15 one were evaluated the reduction of hot Flashes. In herbaceous medicines group, the average of reduction of hot Flashes was 0.85 (CI 95%: 1.83-0.12) lower than the control group which was significant, statistically. The intensity of hot Flashes also significantly reduced. The severe and medium hot Flashes was 0.81( CI 95%: 1.86-0.23) and 0.85 ( CI 95%: 1.83-0.12) lower than control group, respectively which was statistically significant.
Conclusion: Herbaceous Medicines contain phytoestrogens, have a positive effect on reducing the frequency and severity of hot Flashes and They are the best choise for the treatment of hot Flashes in menopausal women and in hormone replacement therapy.


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