Assessment of Dairy Products, Dietary Calcium and Vitamin D Intake in Patients with Breast Cancer

Document Type : Original Article


1 Ph.D. of Nutrition Sciences, Traditional and Complementary, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

2 Lecturer of Anesthesiology, School of Paramedical, Sabzevar University of Medical Sciences, Sabzevar, Iran.


Introduction: Semen is one of the factors in preparing endometrium for embryo implantation. This is in contrast with public believed that immune response to antigen in ejaculated semen will disrupt fertility and pregnancy. The aim of this study was investigation of the influence of seminal plasma injection on Intracytoplasmic Sperm Injection (ICSI) success among infertile couples.
Methods: This clinical trial was conducted on 140 infertile couples undergoing ICSI treatment in Kosar infertility clinic and reproductive health research center of Urmia, Iran during 2010-2011. Couples were randomly divided into seminal plasma injection and control groups. Cry preserved seminal plasma was prepared 30-60 minutes before embryo transferring. bHCG test and sonography was performed respectively at day 14 and between 6th to 12th weeks after embryo transfer. Outcomes were compared between two groups. Data were analyzed by SPSS software version 16 and chi-square test. P value less than 0.05 was considered significant.
Results: There were no significant differences in number of oocyte, quantity and quality of transferred embryo between two groups (p>0.05). Rate of implantation based onβHCG results were 24.3% (17 women) in intervention group and 25.5% (18 women) in control group. Rate of abortion was 18.7% (n=2) and 11.1% (n=3) in intervention and control groups, respectively. There were no significant differences in implantation rate (p=1) and early abortion rate (p=0.5) between two groups.
Conclusion: Intravaginal application of seminal plasma has no effects on fertility outcomes in patients undergoing ICSI treatment.


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