Comparing the Effects of Lidocaine Cream and Mefenamic Acid on Post Episiotomy Pain

Document Type : Original Article

Authors

1 Assistant Professor, Department of Midwifery, School of Nursing and Midwifery, Shahrekord University of Medical Sciences, Shahrekord, Iran.

2 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

Abstract

Introduction: A large number of womensuffered from the post episiotomy pain and the common method for pain relief is oral non-steroidal anti-inflammatory drugs. With considering the adverse effects of these drugs, the aim of present study was to compare the effects of lidocaine cream and mefenamic acid capsule on post episiotomy pain.
Methods: This clinical trial was carried out in 2011 on 60 women with singleton pregnancy at 38-42 weeks of gestation who underwent episiotomy. Cases were randomly divided into both groups and received lidocaine cream and mefenamic acid capsule. Data were collected by questionnaire and Visual Analogue Scale. Pain intensity was compared with the first complaint of mother and 6, 12 and 24 hours after the delivery in both groups. Data were analyzed by SPSS software (version 16), t-test and paired t-test. P value less than 0.05 was considered significant.
Results: With the first complaint of women, the mean of pain intensity was 4.92±1.9 in lidocaine group and 4.90±1.5 in mefenamic acid group that was not significant (p=0.20). Mean intensity of post episiotomy pain in two groups receiving lidocaine cream and mefenamic acid capsule were not significant at hours 6 (3.26±1.3 vs. 3.10±1.6, p=0.05), 12 (2.26±1.7 vs. 2.86±1.4, p=0.36) and 24 (1.46±1.2 vs. 1.49±1.2, p=1) after delivery.
Conclusion: The effects of lidocaine cream and mefenamic acid capsule in relief of post episiotomy pain were similar. With considering the side effects of mefenamic acid, lidocaine cream is an appropriate alternative drug in relief of post episiotomy pain.

Keywords

References

  1. Albers LL, Borders N.Minimizing genital tract trauma and related pain following spontaneous vaginal birth.J Midwifery Womens Health. 2007 May-Jun;52(3):246-53.
  2. Akhlaghi Farideh, Alipour Toktam. Comparison of Suppository Diclofenac and Oral Acetaminophen Codeine in Pain Relief after Episiotomy. The Iranian Journal of Obstetrics, Gynecology And Infertility 2010;13(5): 20-40.
  3. Minassian VA, Jazayeri A, Prien SD, Timmons RL, Stumbo K. Randomized trial of lidocaine ointment versus placebo for the treatment of postpartum perineal pain.Obstet Gynecol. 2002 Dec;100(6):1239-43.
  4. Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Williams Obstetrics, 23 th. 2010, chapter 19. Page 569-592.
  5. Corkill A, Lavender T, Walkinshaw SA, Alfirevic Z. Reducing postnatal pain from perineal tears by using lignocaine gel: a double-blind randomized trial. Birth. 2001 Mar;28(1):22-7.
  6. Fyneface-Ogan S, Mato CN, Enyindah CE. Postpartum perineal pain in primiparous women: a comparison of two local anaesthetic agents.Niger J Med. 2006 Jan-Mar;15(1):77-80
  7. Moll R, Derry S, Moore RA, McQuay HJ. Single dose oral mefenamic acid for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2011, Issue 3. Art. No.: CD007553. DOI: 10.1002/14651858.CD007553.pub2.
  8. Moore RA, Derry S, Moore M, McQuay HJ. Single dose oral tiaprofenic acid for acute postoperative pain in adults.Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007542. doi:
  9. Jackson LM, Hawkey CJ. NSAIDs and the GI tract-potential hazards and benefits. Apoptosis. 1999 Oct;4(5):397-402.
  10. Malekpoor P, Shaghaie F, Del azar A, Ghuch zaeh M. Effect of turmeric solution on pain relief after episiotomy in primiparous women. Nursing & Midwifery Journal 2010;4(16): 4-11.
  11. Abdollahi AA, Arya B, Golali Poor MJ, Vakili MA. Evaluation of postoperative analgesic effect of intramuscular Pethedine, compared to Indomethacin and Diclofenac Sodium suppositories in pain relief after inguinal hernioplasty patients. Arak Medical University Journal (Rahavard Danesh) 2003;6(24): 44-40
  12. Shah Hosseini Z , Amin GH.R , Salehi Sormaghi MH , Danesh MM, Abedian K.[ Double blind study of antiprimary dysmenorrhea effects of Vitagnus].J of Mazendaran university of medical sciences.2005 , 15(50):15- 21.(Persian).
  13. Harrison RF, and Brennan M. Comparison of two formulations of lignocaine spray with mefenamic acid in the relief of post-episiotomy pain: a placebo-controlled study. Curr Med Res Opin 1987; 10: 375-379.
  14. Abedzadeh, Z. Sadat, F. Saberi. Effect of Lidocaine Gel in Pain Relieving after Episiotomy. Journal of Babol University of Medical Sciences 2009;11(2): 43-48
  15. Seçkin B, Avşar F, Parlakyiğit E, Aksakal O.Effects of indomethacin suppository and lidocaine pomade for the relief of post-episiotomy pain. -Int J Gynaecol Obstet. 2002 Aug;78(2):159-61.
  16. Abedzadeh, Z. Sadat, F. Saberi. The efficacy of 2% lidocaine gel versus diclofenac suppository in pain reliving after episiotomy. Koomesh, Journal of Semnan University of Medical Sciences 2009;10(4): 301-306.
  17. Modarres M, Mirmohammad-Ali M, Oshrieh Z, Mehran A. [Comparison of the effect of Mefenamic Acid and Matricaria Camomilla Capsules on primary dysmenorrhea (Persian)]. Journal of Babol University of Medical Sciences. 2011;13(3):50-8.
  18. Khodakrami N, Moatar F, Ghahiri A. [The effect of an Iranian herbal drug on primary dysmenorrhoea – A clinical control trial (Persian)]. Ofogh-e-danesh, Journal of Gonabad University of Medical ciences. 2008;14(2):11-9.
  19. Peter EA, Janssen PA, Grange CS, Douglas MJ. Ibuprofen versus acetaminophen with codeine for the relief of perineal pain after childbirth: a randomized controlled trial. CMAJ. 2001 Oct 30;165(9):1203-9.
  20. Harris LR, Roberts L. Treatments for irritable bowel syndrome: patients' attitudes and acceptability. BMC Complement Altern Med. 2008;8:65.

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