Document Type : Review Article
Authors
1
Assistant Professor, Department of Anesthesiology, Faculty of Medicine, Qom University of medical sciences, Qom, Iran.
2
Assistant Professor of Anesthesiology,Department of Anesthesiology and Critical Care, School of Medicine, 5th Azar Hospital, Sayyad Shirazi Hospital Golestan University of Medical Sciences
3
گروه بیهوشی و مراقبت های ویژه، بیمارستان امام خمینی، دانشگاه علوم پزشکی تهران، تهران، ایران.
4
Master of Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.
5
Anesthesiology, Anesthesiology & Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar AbbaS
6
Assistant Professor, Department of Anesthesiology, Anesthesiology & Critical Care and Pain Management Research Center, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
7
Department of Anesthesiology, Intensive Care fellowship, Anesthesiology & Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
8
Assistant Professor of Anesthesiology, Intensive Care fellowship, Anesthesiology & Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
9
Assistant Professor, Department of Anesthesiology, Anesthesiology, Critical Care and Pain Management Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
10.22038/ijogi.2025.75797.5898
Abstract
Introduction: Trying to control postoperative pain in patients undergoing hysterectomy surgery in order to improve faster and reduce the length of hospitalization has always been the focus of gynecological surgeons.
Methodology: In this systematic review study, all the articles that were the result of clinical trials conducted in Iran in both Persian and English languages, without time limit until September 30, 1402, by searching in the databases Scopus, PubMed, Magiran, SID, Medlib, Cochrane, Science Direct and Google Scholar search engine were reviewed. In order to search for articles in Persian sources, the keywords hysterectomy, abdominal hysterectomy, pain, spinal anesthesia, general anesthesia were used, and in English sources, the keywords Hysterectomy, abdominal hysterectomy, pain, spinal anesthesia, general anesthesia, with all their possible combinations were used.
Results: Among the reviewed articles, 32 studies were selected. A total of 2688 patients were included in the studies. Pain measurement criterion was VAS measurement tool in 29 studies and NRS in 3 studies. The most investigated drugs in studies related to gabapentin and ketamine with 7 studies and the least related to drugs; clonidine, dexamethasone, magnesium oxide, diclofenac, tramadol, morphine, dexmedetomidine, tizanidine and naproxen with 1 study.
Conclusion: The results of this study showed that gabapentin drug can reduce hysterectomy after surgery. It seems that this drug can be used as a suitable alternative to opioids in hysterectomy surgery.
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