Document Type : Case report
Authors
1
Resident, Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2
Medical Student, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3
Radiologist, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4
Assistant Professor, Department of Obstetrics and Gynecology, Research Core on Family Support and Youth Population, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
10.22038/ijogi.2025.85904.6351
Abstract
Introduction: Idiopathic neonatal arterial calcification (IIAC) is a rare disease with an autosomal recessive inheritance pattern that results in widespread calcification in medium and large arteries and can lead to adverse outcomes. In this study, a case of a fetus with IIAC is presented.
Case presentation: A 32-year-old mother with a history of giving birth to a healthy and live baby, a record of one infant death due to cardiac problems and a history of one miscarriage referred to Ommol Banin Hospital in her fourth pregnancy with 30 weeks gestation. Ultrasound examinations revealed multiple cardiac, pulmonary, and renal problems as well as some degree of intrauterine growth restriction (IUGR) for the fetus that strongly suggested idiopathic neonatal arterial calcification (IIAC). Ultimately, due to the mother's severe preeclampsia, delivery was performed and a male infant was born with an Apgar score of 3-6 that as predicted, despite resuscitation, the infant died a few hours after birth.
Conclusion: Diagnosing this disease during pregnancy, especially during ultrasound examinations of fetal abnormalities, requires high accuracy and awareness of this rare disorder. Early and accurate diagnosis of this disease can play an important role in clinical decisions related to the continuation of pregnancy, selection of treatment methods, and assessment of the newborn's prognosis. Physician awareness of this disease and careful imaging studies can help in timely diagnosis and better management of this rare disorder, ultimately leading to improved quality of prenatal care. Also, considering this diagnosis can play an important role in counseling parents to make informed decisions about future pregnancies.
Keywords
Main Subjects
)