Evaluation of fetal and maternal complications of IVF pregnancies based on donated and non-donated oocytes: a single-center retrospective study.

Articles in Press

Document Type : Original Article

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hemat street

10.22038/ijogi.2025.83595.6242

Abstract

Abstract

Introduction: The use of donated eggs is one of the strategies used for patients. In this study, we investigated the relationship between autologous and donation of oocytes with maternal and neonatal complications.



Materials and Methods: Expressing the collection of information on a checklist including the variables of maternal complications (pre-eclampsia, premature labor (with maternal causes, with fetal causes, due to premature rupture of membranes, due to premature labor pain), gestational diabetes, placental abruption, placenta previa) and neonatal complications (baby birth weight, Apgar score, need for NICU admission, need for intubation, need for surfactant, syndrome respiratory distress, meconium aspiration, infant death, stillbirth) were extracted.

Results:

In both groups, the frequency of twinning in fresh eggs was lower compared to frozen eggs (p=0.01). Also, the frequency of preeclampsia, diabetes mellitus, hypertension and placenta previa was lower between the two groups in fresh eggs compared to frozen, but this difference was not statistically significant (p>0.05). The overall average gestational age in the group of non-donated eggs was higher compared to the other group, but this difference was not significant (p>0.05).

The frequency of intra uterine growth restriction (IUGR), large for gestational age (LGA), death, term, NICU administration, and intubation complications were shown in frozen eggs compared to fresh eggs in both groups. was more, however, no statistically significant relationship was observed between them (p>0.05).

Conclusion: The results showed that the frequency of twinning was higher in patients who underwent non-oocyte donation.

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The Iranian Journal of Obstetrics, Gynecology and Infertility

Articles in Press, Accepted Manuscript
Available Online from 19 May 2025

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