The effect of ointment containing jojoba oil on pain intensity of episiotomy wound in primiparous women: A triple-blind clinical trial

Document Type : Original Article

Authors

1 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Professor, Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 M.Sc. of Health and Social Welfare, Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

10.22038/ijogi.2025.84737.6297

Abstract

Introduction: Episiotomy is performed in the perineum to facilitate delivery of the fetus and may cause complications such as pain and inflammation. Jojoba due to its flavonoids and phenolic compounds controls pain centrally by acting on GABA receptors and inhibiting enzymes involved in the brain. The present study was conducted with aim to determine the effect of ointment containing jojoba oil on pain intensity of episiotomy wound in primiparous women.
Methods: This triple-blind cllinical trial was conducted in 2024 on 92 primiparous women referred to Mahdieh Hospital, Tehran (46 in the intervention group and 46 in the placebo group). After delivery, for 10 days, every 12 hours, ointment for local use on the incision area was prescribed for both study groups. Data collection tools include demographic questionnaire, obstetrics and gynecology information checklist, health status form and visual analog scale. Data analysis was done using SPSS statistical software (version 21)  and chi-square, independent t, Fisher's exact and two-way ANOVA. P<0.05 was considered significant.
Results: There was a statistically significant difference between the use of ointment containing jojoba oil and pain in general in 3 measurement modes (p<0.001), and 71.1% of the changes made in the pain variable was due to the use of ointment containing jojoba oil. Comparing the mean wound healing in three stages showed that the trend of pain reduction in the intervention group on the 5th day after delivery and the 10th day after delivery was more than the control group (p=0.001).
Conclusion: Ointment containing jojoba oil reduces the intensity of pain caused by episiotomy in primiparous women.

Keywords

Main Subjects

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 28, Issue 3
May 2025
Pages 26-38

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