Investigating the Relationship between Pregnancy Complications and Polycystic Ovary Syndrome

Document Type : Original Article

Authors

1 Associate Professor, Department of Obstetrics and Gynecology, Fatemehzahra Fertility and Reproductive Health Research Center, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

2 Associate Professor, Department of Obstetrics and Gynecology, Stemcell Research Center, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

3 Professor, Department of Obstetrics and Gynecology, Fatemehzahra Fertility and Reproductive Health Research Center, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

4 Medical Student, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Abstract

Introduction: Polycystic ovary syndrome (PCOS) is one of the most widespread illnesses of endocrine system in women at reproductive age. The Other studies have shown PCOS as a risk factor to increase the prevalence of pregnancy complications such as pre-eclampsia and gestational diabetes. The aim of this study was to compare the pregnancy outcome in women with and without PCOS.
Methods: This case-control study was conducted on 120 pregnant women with and without PCOS syndrome who referred to Fatemeh Alzahra infertility clinical center and Ayattolah Rohani hospital since 2010 to 2012 in Babol, Iran. Demographic information and maternal and neonatal outcomes of two groups were extracted from the files of patients and recorded in a questionnaire. Data were analyzed by SPSS software (version 18), chi-square test and t-test. P value less than 0.05 was considered significant.
Results: 60 women of 120 participants had PCOS and 60 women had not. The mean age of PCOS group was 26.4±9.42 and control group was 26.18±5.43 years, that was not significant (p=0.81). In pregnancy complications, there was no significant differences between two groups in terms of the ratio of intra uterine fetal death (p=0.09), intra uterine growth restriction (p=0.59) and neonatal weight (p=0.1). Preterm labor was seen in 16 women of PCOS group (32%) and 7 women of control group (11.7%) that the difference was significant (p=0.009). 10 cases of abortion occurred in PCOS group and 2 cases in control group that the difference was significant (p=0.001).
Conclusion:  Some pregnancy complications such as abortion and preterm labor were seen more in women with PCOS who need more attention during pregnancy.

Keywords

References

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