Comparative study of pregnancy outcomes and success rates in fresh and frozen embryo transfer cycles

Document Type : Original Article

Authors

1 Department of Obstetrics and Gynecology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

2 Department of Obstetrics and Gynecology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

3 Clinical Research Development Center of Imam Reza Hospital, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

4 School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran

5 Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran

6 Department of Reproductive Health, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran

10.22038/ijogi.2024.79412.6073

Abstract

Introduction: Today, although the knowledge about the success rate of Assisted reproductive technologies has increased dramatically, but a detailed comparison regarding whether embryo freezing improves the outcomes of embryo transfer cycles? It has not been done, so the aim of this study is to compare pregnancy outcomes and success rates in fresh and frozen embryo transfer cycles.

Methods: The current study is a cross-sectional analytical study. The subjects were infertile couples who were candidates for embryo transfer, referring at Motazedi and Jahad University Infertility treatment centers in Kermanshah, the first group of couples with fresh embryo transfer and the second group were couples who were candidates for frozen embryo transfer. Mothers and their neonates were followed up until after birth. At the end, the data was analyzed through SPSS statistical software.



Results: 130 infertile couples were investigated in two groups of frozen embryo transfer (n=100) and fresh embryo transfer (n=30). The rate of chemical and clinical pregnancy was higher in the frozen embryo transfer group. As the most common pregnancy outcomes, early abortion in the frozen embryo transfer group and premature birth, late abortion was more in the fresh embryo transfer group. Also, there was no statistically significant difference between the two groups in terms of neonatal growth parameters, including weight, average height and term of IUGR.

Conclusion: Frozen embryo transfer increases the rate of chemical and clinical pregnancy, but it does not have a significant effect on the birth of IUGR neonates and the growth parameters of newborns.

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