Frequency of Congenital Heart Diseases in Infants with Imperforate Anus and Esophageal Atresia Hospitalized in NICUs of Khorramabad Teaching Hospitals from 2016 to 2020

Document Type : Original Article

Authors

1 Medical Student, Student Research Committee, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

2 Medical Student, Student Research Committee, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. Medical Student, USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran.

3 Assistant Professor, Department of Biostatistics and Epidemiology, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.

4 Assistant Professor of Neonatal-Perinatal Medicine, Department of Pediatrics, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

10.22038/ijogi.2024.78225.6012

Abstract

Introduction: The frequency of congenital heart disease (CHD) is higher in people with gastrointestinal abnormalities compared to the normal population. Treatment of these patients may be difficult if there is a simultaneous abnormality. The association of CHD with imperforate anus or esophageal atresia can have a significant impact on the treatment and prognosis of these infants. The present study was conducted with aim to investigate the frequency of congenital heart disease in infants with imperforate anus and esophageal atresia admitted to the neonatal intensive care unit (NICU).
Methods: In this study, the files of 47 infants with imperforate anus or esophageal atresia admitted to the NICU of Khorramabad teaching hospitals between 2016 and 2020 were reviewed. The frequency of congenital disease, demographic characteristics, and some possible risk factors were investigated in the files of these babies. Data were analyzed using SPSS software (version 25) and Fisher Exact test and Independent t-test. P<0.05 was considered significant.
Results: The frequency of congenital heart disease in infants with imperforate anus and esophageal atresia was high (70.7%). The most common type of congenital heart disease in this study was atrial septal defect (ASD) (55.1%), followed by ventricular septal defect (VSD) (20.7%), patent ductus arteriosus (PDA) (13.8%), ASD+PDA (6.9%), and ASD+ transposition of the great vessels (TOGV) (3.5%).
Conclusion: The frequency of congenital heart disease in infants with imperforate anus and esophageal atresia is high. Since congenital heart disease can increase the mortality of these infants, therefore, diagnosis of this anomaly plays an important role in the management of these patients.

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