The Effect of High-Intensity Interval Training and Thyme Supplementation on the Serum Levels Adropin and Tumour Necrosis Factor alpha in Sedentary Young Girls: A Quasi-Experimental Study

Document Type : Original Article

Authors

1 PhD Student, Department of Sports Physiology, Tehran North Branch, Islamic Azad University, Tehran, Iran.

2 Professor, Department of Exercise Physiology, Tehran North Branch, Islamic Azad University, Tehran, Iran.

3 Assistant Professor, Department of Sports Physiology, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran.

Abstract

Introduction: Inactivity and sedentary are of the most important health problems that can affect serum proteins. The present research was conducted with aim to investigate the effect of eight weeks of high-intensity interval training (HIIT) along with the consumption of thyme suplementation on the serum levels of adropin and Tumour Necrosis Factor alpha (TNF-α) in sedentary young girls.
Methods: In this quasi-experimental study conducted in 2023, 48 sedentary young girls with mean age of 20.00±1.61 years were randomly divided into four groups: HIIT, thyme, HIIT+thyme and control. Venous blood was taken in the pre-test and post-test stages. Serum levels of adropin and TNF-α were analyzed using specific ELISA kits. The data was analyzed by SPSS statistical software (version 22) using ANOVA and paired t tests. P<0.05 was considered statistically significant.
Results: There was no significant difference between the studied groups in the serum level of adropin before the test (P=0.501) and after the test (P=0.732), and the changes in adropin were not significant in the studied groups (P>0.05). A significant decrease in TNF-α values was observed in the thyme (P=0.001) and HIIT + thyme groups (P=0.014) after the interventions, while a significant increase in TNF-α values was observed in the HIIT group (P=0.007).
Conclusion: Performing HIIT exercises increases TNF-α levels and consuming thyme supplements decreases it and in cases where they are used at the same time, the effect of thyme is still stronger. Adropin levels were not affected by exercise or thyme supplementation.

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References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 5
July 2024
Pages 20-31

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