تأثیر تمرین تناوبی شدید و مصرف مکمل آویشن بر سطوح سرمی آدروپین و فاکتور نکروز دهنده تومور آلفا در دختران جوان کم‌تحرک: یک مطالعه نیمه‌تجربی

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی دکتری تخصصی، گروه فیزیولوژی ورزشی، واحد تهران شمال، دانشگاه آزاد اسلامی، تهران، ایران.

2 استاد، گروه فیزیولوژی ورزشی، واحد تهران شمال، دانشگاه آزاد اسلامی، تهران، ایران.

3 استادیار، گروه فیزیولوژی ورزشی، واحد اسلامشهر، دانشگاه آزاد اسلامی، اسلامشهر، ایران.

چکیده

مقدمه: کم ­تحرکی و بی­ تحرکی، یکی از معضلات مهم سلامتی است که می ­تواند پروتئین­ های سرم را متأثر کند. مطالعه حاضر با هدف بررسی تأثیر 8 هفته تمرین تناوبی شدید (HIIT) به همراه مصرف مکمل آویشن بر سطوح سرمی آدروپین و فاکتور نکروز دهنده تومور آلفا (TNF-α) در دختران جوان کم­تحرک انجام شد.
روش‌کار: در این مطالعه نیمه ­تجربی که در سال 1402 انجام شد، 48 دختر جوان کم‌تحرک با میانگین سنی 61/1±00/20 سال به‌صورت تصادفی به چهار گروه تمرین HIIT، آویشن، HIIT +آویشن و گروه کنترل تقسیم شدند. در مرحله پیش ­آزمون و پس ­آزمون خون وریدی اخذ شد. سطح سرمی TNF-α و آدروپین با استفاده از کیت­ های الایزا اختصاصی آنالیز شدند. تجزیه و تحلیل داده­ ها با استفاده از نرم ­افزار آماری SPSS (نسخه 22) و آزمون­ های آماری آنووا و تی جفت شده انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته ­ها: سطح سرمی آدروپین پیش از آزمون (501/0=p) و پس از آزمون (732/0=p) بین گروه ­های مورد مطالعه تفاوت معنی­ داری نداشت و تغییرات آدروپین در گروه­ ها معنی­ دار نبود (05/0p>). کاهش چشمگیر مقادیر TNF-α در گروه­ های آویشن (001/0=p) و HIIT +آویشن (014/0=p) پس از انجام مداخلات گزارش شد. افزایش چشمگیر مقادیر TNF-α در گروه HIIT (007/0=p) مشاهده گردید.
نتیجه ­گیری: انجام تمرینات HIIT موجب افزایش سطح TNF-α و مصرف مکمل آویشن، موجب کاهش سطح این سیتوکین می­ شود و در مواردی که همزمان مورد استفاده قرار گیرند، باز هم اثر آویشن قوی ­تر است. سطح آدروپین تحت تأثیر تمرینات یا مصرف مکمل آویشن قرار نگرفت. 

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of High-Intensity Interval Training and Thyme Supplementation on the Serum Levels Adropin and Tumour Necrosis Factor alpha in Sedentary Young Girls: A Quasi-Experimental Study

نویسندگان [English]

  • Zahra Mohseni 1
  • Bahram Abedi 2
  • Yaser Kazemzadeh 3
1 PhD Student, Department of Sports Physiology, Tehran North Branch, Islamic Azad University, Tehran, Iran.
2 Professor, Department of Exercise Physiology, Tehran North Branch, Islamic Azad University, Tehran, Iran.
3 Assistant Professor, Department of Sports Physiology, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran.
چکیده [English]

Introduction: Inactivity and sedentary are of the most important health problems that can affect serum proteins. The present research was conducted with aim to investigate the effect of eight weeks of high-intensity interval training (HIIT) along with the consumption of thyme suplementation on the serum levels of adropin and Tumour Necrosis Factor alpha (TNF-α) in sedentary young girls.
Methods: In this quasi-experimental study conducted in 2023, 48 sedentary young girls with mean age of 20.00±1.61 years were randomly divided into four groups: HIIT, thyme, HIIT+thyme and control. Venous blood was taken in the pre-test and post-test stages. Serum levels of adropin and TNF-α were analyzed using specific ELISA kits. The data was analyzed by SPSS statistical software (version 22) using ANOVA and paired t tests. P<0.05 was considered statistically significant.
Results: There was no significant difference between the studied groups in the serum level of adropin before the test (P=0.501) and after the test (P=0.732), and the changes in adropin were not significant in the studied groups (P>0.05). A significant decrease in TNF-α values was observed in the thyme (P=0.001) and HIIT + thyme groups (P=0.014) after the interventions, while a significant increase in TNF-α values was observed in the HIIT group (P=0.007).
Conclusion: Performing HIIT exercises increases TNF-α levels and consuming thyme supplements decreases it and in cases where they are used at the same time, the effect of thyme is still stronger. Adropin levels were not affected by exercise or thyme supplementation.

کلیدواژه‌ها [English]

  • Adropin
  • High-intensity interval training
  • Sedentary
  • Thyme
  • TNF-α

مراجع

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مجله زنان، مامایی و نازایی ایران
دوره 27، شماره 5
مرداد 1403
صفحه 20-31

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