Document Type : Review Article
Authors
1
M.Sc. Student of Food Science, Student Research Committee, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2
Assistant Professor of Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
10.22038/ijogi.2024.80938.6131
Abstract
Introduction: Male infertility is a significant global issue affecting men's health, characterized by dysfunction or suboptimal performance of components of the male reproductive system. Nutritional factors can play a crucial role in either promoting or impairing fertility, with the impact being dictated by the quality and quantity of food intake. The purpose of this systematic review is to investigate the effects of monosodium glutamate consumption on sperm quantity, concentration, morphology, and motility in male rats.
Methods: A systematic search was conducted on English and Persian Medline databases, Embase, Google Scholar, Web of Science, Science Direct, Scopus, Magiran, SID, ISC, and Cochrane from January 2010 to May 2023. Keywords related to male infertility, monosodium glutamate, male rats, sperm count, live sperm, sperm morphology, and sperm motility were utilized in the search.
Results: Fourteen studies were included in this systematic review. Findings indicated that monosodium glutamate consumption was associated with decreased sperm count, live sperm percentage, and alterations in sperm morphology in male rats. Most studies reported a decrease in sperm motility with monosodium glutamate intake, although some studies observed an increase in sperm motility.
Conclusion: Increased consumption of monosodium glutamate is linked to reductions in sperm quantity, concentration, and motility in male rats, potentially contributing to elevated infertility rates. Prolonged and high-dose exposure to monosodium glutamate may significantly impact sperm characteristics, highlighting the need for further research on its effects on male fertility.
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