Document Type : Review Article
Authors
1
Anesthesiology, Anesthesiology & Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar AbbaS
2
استادیار گروه زنان، مرکز تحقیقات سلامت و بیماری های زنان، دانشگاه علوم پزشکی جهرم، جهرم، ایران.
3
Assistant Professor, Department of Anesthesiology, Anesthesiology & Critical Care and Pain Management Research Center, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
4
Assistant Professor of Surgery Department of Surgery, School of Medicine, Hormozgan University of Medical Sciences
5
استادیار گروه بیهوشی، مرکز تحقیقات بیهوشی، مراقبت ویژه و کنترل درد، دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران.
6
Assistant Professor of Anesthesiology, Intensive Care fellowship, Anesthesiology & Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
7
کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شیراز، شیراز، ایران.
8
Assistant Professor of Surgery, Department of Surgery, Peymanie Hospital, Jahrom University of Medical Sciences
9
Assistant Professor of Anesthesiology,Department of Anesthesiology and Critical Care, School of Medicine, 5th Azar Hospital, Sayyad Shirazi Hospital Golestan University of Medical Sciences
10.22038/ijogi.2024.79425.6068
Abstract
Introduction: While multiple systematic review studies are performed on the effects and side effects of the dexmedetomidine in gynecology surgeries, no previous review has evaluated its effects on the occurrence of the ileus. So, in this review we aimed at collecting data about this medical entity in literature of dexmedetomidine and gynecology surgery.
Methods: A systematic review of databases of PubMed, Scopus, Embase, Web of Science, CINAHL, Cochrane Library, ClinicalTrials.gov, WHO International Clinical Trials Registry Platform (ICTRP), Iranian Database of Medical Sciences (IranMedex), and Scientific Information Database (SID) were conducted using set of keywords about ileus, gynecology surgeries, and Dexmedetomidine. Data were extracted and outcomes regarding the bowel function recovery were pooled by random effect models of Cohen’s D.
Results: a total of 9 studies met the eligibility criteria. The meta-analysis results comparing the time of recovery of bowel function after surgery between Dexmedetomidine and control showed that there is a less time to recover the bowel function in DEX groups compared to controls, with the total effect size of -1.974, 95% CI was [-3.707, -0.242].
Conclusion: Dexmedetomidine seems to be accelerating bowel function recovery post-gynecology surgery, warranting further research for comprehensive understanding and clinical application.
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