Document Type : Review Article
Authors
1
B.Sc. Student of Nutrition Sciences, Student Research Committee, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2
M.Sc. Student of Clinical Nutrition, Student Research Committee, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3
Assistant Professor of Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
10.22038/ijogi.2024.78337.6018
Abstract
Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects many women of reproductive age. This systematic review aimed to determine the effects of the Dietary Approaches to Stop Hypertension (DASH) diet on metabolic outcomes, oxidative stress, inflammatory factors and sex hormones in patients with PCOS.
Methods: In this systematic review, keywords related to PCOS, lipid profile, glycemic status, anthropometric factors, oxidative stress, inflammatory factors, sex hormones, and DASH were searched in various databases including Medline, Scopus, Embase, Science Direct, Magiran, ISD, ISC, and Cochrane in both Farsi and English languages up until January 2024.
Results: Four original research articles with a clinical trial design and an intervention period of 8-12 weeks using the DASH diet in PCOS patients were analyzed. The findings of these studies showed that following the DASH diet led to weight loss, reduced body mass index, waist circumference, and hip circumference. It also resulted in lower serum levels of triglycerides, very low density lipoproteins, insulin resistance, androstenedione, antimullerin hormone, free androgen index, malondialdehyde, and high-sensitivity C-reactive protein. Additionally, it was associated with improved sensitivity to insulin, increased total plasma antioxidant capacity, higher levels of total glutathione, sex hormone-binding globulin, and nitric oxide in the blood.
Conclusion: Following the DASH diet has shown to have positive effects on various health outcomes in individuals with PCOS, including weight loss, improved lipid profile, antioxidant status, sex hormones, insulin sensitivity, and markers of oxidative stress and inflammation.
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