The effect of menstrual phases on hemodynamic changes of patients during laparoscopic cholecystectomy surgery

Document Type : Original Article

Authors

1 Associate Professor, Department of Anesthesiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

2 Assistant Professor, Department of anesthesiology, Faculty of medicine, Tabriz University of Medical Sciences, Islamic Azad University, Tabriz, Iran.

3 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

4 Assistant Professor, Department of general surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

10.22038/ijogi.2024.75937.5906

Abstract

Introduction: There are contradictory results regarding the effects of the menstrual cycle on changes in blood pressure, heart rate, ventilation, and oxytocin hormone during anesthesia in patients who are candidates for laparoscopic cholecystectomy surgery. Therefore, the present study was performed with aim to investigate the effect of menstrual phases on the hemodynamic changes of patients during laparoscopic cholecystectomy.
Methods: This cross-sectional descriptive study was conducted in 2018 on 100 patients who were candidates for laparoscopic cholecystectomy referred to Imam Reza Hospital (affiliated to Tabriz University of Medical Sciences). Patients were divided into two groups: luteal phase and follicular phase. Hemodynamic parameters, including heart rate, blood pressure, arterial oxygen saturation, and end-expiratory CO2 were compared between these groups. Demographic information and hemodynamic status before and during anesthesia were recorded in a researcher-made checklist. Data analysis was performed using SPSS software (version 22) and t-test, chi-square, and repeated measures tests. P<0.05 was considered statistically significant.
Results: According to the results of t-test, there was no statistically significant difference between the two groups at any time in the mean arterial pressure, end-expiratory CO2, and arterial oxygen saturation (P>0.05). However, according to the results of repeated measures tests, the mean arterial pressure changes during the study were significantly higher in the follicular phase group (P=0.031) than in the luteal phase group (P=0.059). Also, according to the results of t-test, the comparison of the heart rate status between the two groups did not show a significant statistical difference at any time (P˃0.05); However, according to the results of repeated measures tests, heart rate changes during the study were significantly higher in the follicular phase group (P=0.019) than in the luteal phase group (P=0.126).
Conclusion: Menstrual cycle significantly affects hemodynamic parameters during anesthesia in patients undergoing laparoscopic cholecystectomy. These changes are more pronounced during the follicular phase compared to the luteal phase.

Keywords

Main Subjects

References

  1. Maroufi P, Moradi A, Zamani M, Dehghani A, Akhuleh OZ. Effectiveness of the Early Strengthening of the Thigh Muscles on the Outcomes of Anterior Cruciate Ligament Reconstruction (ACL-R): A Randomized Clinical Trial. Bahrain Medical Bulletin 2023; 45(2):1416-20.
  2. Bilehjani E, Fakhari S, Farzin H, Yaghoubi A, Mirinazhad M, Shadvar K, et al. The correlation between preoperative erythrocyte sedimentation rate and postoperative outcome in adult cardiac surgery. International journal of general medicine 2017: 15-21.
  3. Rousta F, Dadashzadeh M, Mahdavi F, Nasseri AR. Lymph Node Involvement and Related Risk Factors in Patients With Breast Cancer Referred for Radiotherapy: A 20-Year Study on 15 000 Women. International Journal of Women's Health & Reproduction Sciences 2021; 9(3).
  4. Mahdavi F, Owaysee Osquee H. Comparison of serum levels of vitamin D after mastectomy in women with and without postoperative infection: case-control study. The Iranian Journal of Obstetrics, Gynecology and Infertility 2020; 23(3):33-8.
  5. Charsouei S, Esfahlani MZ, Dorosti A, Zamiri RE. Effects of COVID-19 pandemic on perceived stress, quality of life, and coping strategies of women with breast cancer with spinal metastasis under chemotherapy. Int J Womens Health Reprod Sci 2021; 9(1):55-60.
  6. Barakchian SN, Shati M, Mortazavi SS, Nikanfar M, Charsouei S. Psychometric properties of the Persian version of the Patient-Weighted Quality of Life in Epilepsy Inventory-10-P. Epilepsy & Behavior 2020; 111:107243.
  7. Nezafati S, Dehghani AA, Khiavi RK, Mortazavi A, Ebrahimi L. Opioid requirement and pain intensity after mandibular surgeries with dexmedetomidine administration in two ways: intraoperative infusion versus bolus injection. Oral and Maxillofacial Surgery 2023: 1-7.
  8. Jiang S, Zhang Y, Alsaikhan F, Jalil AT, Gol MK, Tarighatnia A. A meta-analysis review of the effect of Zn-doped synthetic polymer materials on bone regeneration. Journal of Drug Delivery Science and Technology 2022; 76:103792.
  9. Ghomeishi A, Mohtadi AR, Behaeen K, Nesioonpour S, Bakhtiari N, Fahlyani FK. Comparison of the effect of propofol and dexmedetomidine on hemodynamic parameters and stress response hormones during laparoscopic cholecystectomy surgery. Anesthesiology and Pain Medicine 2021; 11(5).
  10. Bilehjani E, Fakhari S, Farzin H, Yaghoubi A, Mirinazhad M, Shadvar K, et al. The correlation between preoperative erythrocyte sedimentation rate and postoperative outcome in adult cardiac surgery. International journal of general medicine 2017: 15-21.
  11. Khanbabayi Gol M, Eidy M, Zamani Esfahlani M. Frequency ratio of carpal tunnel syndrome in women with breast cancer treated with lymphedema in Tabriz medical education centers; 2018-2019. The Iranian Journal of Obstetrics, Gynecology and Infertility 2020; 22(12):62-8.
  12. Haghdoost SM, Gol MK. The necessity of paying more attention to the neurological and psychological problems caused by the COVID-19 pandemic during pregnancy. Health 2020; 3(4).
  13. Serban D, Socea B, Balasescu SA, Badiu CD, Tudor C, Dascalu AM, et al. Safety of laparoscopic cholecystectomy for acute cholecystitis in the elderly: A multivariate analysis of risk factors for intra and postoperative complications. Medicina 2021; 57(3):230.
  14. Binazir MB, Alizadeh M, Bayrami HJ, Azhough R, Movassaghi R, Nikasa P. The effect of a modified world health organization surgical safety checklist on postoperative complications in a tertiary hospital in iran. Iranian Journal of Public Health 2015; 44(2):292.
  15. Rostami F, Osquee HO, Mahdavi F, Dousti S. Development of a new psychometric assessment tool for predicting hepatitis B virus infection in pregnant women. Int J Women’s Health Reprod Sci 2020; 8(3):297-302.
  16. Lu M, Bi J, Li Y, Hao Z. Effect of obesity on venous hemodynamics of the lower limbs during laparoscopic cholecystectomy. Phlebology 2022; 37(5):381-5.
  17. Rezaei S, Naghipour B, Rezaei M, Dadashzadeh M, Sadeghi S. Chemical evaluation of gastrointestinal, coronary and pulmonary complications in patients admitted to the intensive care unit. Eurasian Chemical Communications 2022; 4(6):557-66.
  18. Mahdavi F, Haghdoost M. Comparative study of the role of zinc in the scar recovery after abdominal hysterectomy in women with and without cancer and its relation with anthropometric indices of women referred to Tabriz hospitals: A case-control study. The Iranian Journal of Obstetrics, Gynecology and Infertility 2020; 23(4):24-30.
  19. Ozturk P. The Relationship of Patient's Mobility Levels who Had Laparoscopic Cholecystectomy with Pain and Hemodynamic Parameters. International Journal of Caring Sciences 2023; 16(2):664-76.
  20. Sayyah-Melli M, Zonoozi GK, Hashemzadeh S, Esfahani A, Ouladehsahebmadarek E, Shobeiry MJ, et al. Comparison of platinum-based neoadjuvant chemotherapy and primary debulking surgery in patients with advanced ovarian cancer. The Journal of Obstetrics and Gynecology of India 2013; 63:405-9.
  21. Aslanabadi S, Azhough R, Motlagh PS, Hadidchi S, Tabrizi AD, Zonouzy KK. Intramedullary spinal cord ganglioglioma presenting with abnormal abdominal wall movement: case report. Neurosurgical focus 2004; 17(4):1-2.
  22. Gautam S, Prakash V, Mishra N, Prakash R, Kumar S, Jafa S. Effect of two different doses of dexmedetomidine on the hemodynamics of “Hypertensive Patients” undergoing laparoscopic cholecystectomy. Anesthesia Essays and Researches 2020; 14(3):401-5.
  23. Ghojazadeh M, Paknezhad SP, Mohammadzadeh S, Vahed N, Rajabpour ZV, Rezaee M, et al. Dexmedetomidine for procedural sedation in the emergency department: a systematic review. Shiraz E-Medical Journal 2022; 23(1).
  24. Eghdam-Zamiri R, Khanbabayi Gol M. Effects of ginger capsule on treatment of nausea and vomiting in patients receiving cisplatin undergoing mastectomy: a randomized clinical trial. The Iranian Journal of Obstetrics, Gynecology and Infertility 2020; 22(11):15-21.
  25. Zou L, Miao S, Wang L, Wang G. Effects of menstrual cycle on nausea and vomiting after general anesthesia. Journal of anesthesia 2020; 34:519-26.
  26. Tófoli GR, Ramacciato JC, Volpato MC, Meechan JG, Ranali J, Groppo FC. Anesthetic efficacy and pain induced by dental anesthesia: the influence of gender and menstrual cycle. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 2007; 103(2):e34-8.
  27. Lin H, Li WZ. Effect of the menstrual cycle on circulation during combined spinal-epidural anaesthesia. BMC anesthesiology 2018; 18:1-6.
  28. Kenig J, Richter P, Sikora Ł. Menstruation-still a contraindication to elective surgery?. Polish Journal of Surgery 2014; 86(1):57-9.
  29. reza Moradkhani M, Karimi A, Zarei Z, Vahabi S. The relationship between the phases of the menstrual cycle on the incidence and severity of headache after spinal anesthesia. The Surgery Journal 2019; 5(03):e126-30.
  30. Erden V, Yangn Z, Erkalp K, Delatioglu H, Bahçeci F, Seyhan A. Increased progesterone production during the luteal phase of menstruation may decrease anesthetic requirement. Anesthesia & Analgesia 2005; 101(4):1007-11.
  31. Hanc V, Yurtlu S, Hakimoglu S, Ylmaz M, Ayoglu H, Basaran M, et al. The effects of the menstrual cycle on the hemodynamic response to laryngoscopy and tracheal intubation. Anesthesia & Analgesia 2010; 111(2):362-5.
  32. Kurdi MS, Ramaswamy AH. Does the phase of the menstrual cycle really matter to anaesthesia?. Indian journal of anaesthesia 2018; 62(5):330-6.
  33. Piroli A, Mattei A, Carta G, D'Alfonso A, Palermo P, Marinangeli F, et al. Influence of the menstrual cycle phase on pain perception and analgesic requirements in young women undergoing gynecological laparoscopy. Pain Practice 2019; 19(2):140-8.
  34. Ileri Z, Baka Z, Akin M, Apiliogullari S, Basciftci F. Effect of menstrual cycle on orthodontic pain perception. Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie 2016; 77(3).
  35. Bollucuoglu K, Hanci VO, Yurtlu S, Okyay D, Ayoglu H, Turan IO. Comparison of propofol-dexmedetomidine, tiopental-dexmedetomidine and etomidate-dexmedetomidine combinations' effects on the tracheal intubation conditions without using muscle relaxants. Bratislavske lekarske listy 2013; 114(9):514-8.
The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 2
April 2024
Pages 17-26

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