Infertility registry data of infertile couples in southern Iran: 2017-2022

Document Type : Original Article

Authors

1 Associate Professor, Department of Obstetrics and Gynecology, Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

2 Associate Professor, Department of Midwifery, Mother and Child Care Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. Rayan Stem Cells and Regenerative Medicine Research Center, Ravan Sazeh Company, Tehran, Iran.

3 Department of Midwifery, School of Nursing and Midwifery, Ardabil University of Medical Sciences, Ardabil, Iran. Ph.D Student of Reproductive Health, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.

4 Assistant Professor, Department of Midwifery, Mother and Child Care Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

5 B.Sc.in Midwifery, Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

6 Instructor, Department of Midwifery, School of Nursing and Midwifery, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.

Abstract

Introduction: Infertility causes serious damage to the reproductive health system. It has been decided that all countries should include infertility in priority programs related to reproductive health. The present study was performed with aim to investigate infertility registry data of infertile couples in southern Iran.
Methods: This cross-sectional descriptive and retrospective study was conducted in 2017-2022. The registry data of 634 infertile couples referring to Bandar Abbas infertility center in southern Iran were extracted. The data was collected using the researcher's checklist based on the information in the registry system. The data were analyzed using SPSS software (version 25). P<0.05 was considered statistically significant.
Results: Irregular menstrual cycle was recorded in 171 cases (26.97%). Among the referring women, 61 cases (9.62%) had dyspareunia, 37 (5.83%) galactorrhea, 322 (50.79%) hirsutism and 141 (22.24%) dysmenorrhea. Among the referring couples, 257 cases (40.54%) were due to female causes and 189 (29.81%) male causes, and 156 (24.60%) had infertility due to unknown causes, and 32 (5.05%) had problems with both couples. The most common female causes of infertility were reduced ovarian reserve (35.40%), polycystic ovary syndrome (PCOS) (34.63%), fallopian tube obstruction (10.11%), hydrosalpinx (3.50%), endometriosis (6.61%), and other cases (9.72%), respectively.
Conclusion: The female factors are one of the important factors causing infertility, followed by male factors. Considering the effect of some risk factors affecting infertility and the presence of diseases discovered in infertile women, it is possible to increase the probability of pregnancy by correcting underlying diseases and properly managing related factors.

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Main Subjects

References

  1. Moradi S, Mohammadpour S, Ahi Q. The Role of Psychological Distress and Resilience in Quality of Life in Infertility in Infertile Women. Research in Clinical Psychology and Counseling 2021; 11(1):81-100.
  2. Saremi A, Moradzadeh R, Bahrami A. Physical Activity and Body Composition in Infertile and Fertile Women. Journal of Arak University of Medical Sciences 2022; 24(6):888-901.
  3. Wentzell EA, Inhorn MC. Reconceiving masculinity and ‘men as partners’ for ICPD beyond 2014: insights from a Mexican HPV study. Global Public Health 2014; 9(6):691-705.
  4. Alizadeh T, Keshavarz Z, Mirghafourvand M, Zayeri F. Investigation of health promoting lifestyle and social support and their correlation among Iranian women with multiple sclerosis. Int J Women’s Health Reprod Sci 2018; 6(2):167-73.
  5. Australian Institute of Health. Australia's Health 2012: The Thirteenth Biennial Health Report of the Australian Institute of Health and Welfare. AIHW; 2012.
  6. Alimanesh N, Keshavarz Z, Riazi H, Heidar Z, Nasiri M. The Sexual Satisfaction Level and Related Factors in Infertile Couples with Female Infertility. Journal of Isfahan Medical School 2020; 38(599):842-8.
  7. Dezhkam L, Tafvizi MD, Kalani N. Different dimensions of infertility phenomenon in the life of Iranian women: a systematic review study. Iranian Journal of Obstetrics, Gynecology and Infertility 2023; 26(3):90-108.
  8. Bahrami-Kerchi A, Manshaee G, Keshtiaray N. The effectiveness of psychological empowerment therapy and dialectical behavior therapy on infertility stress of infertile women in pretreatment stage of in vitro fertilization. Feyz Medical Sciences Journal 2020; 24(5):554-64.
  9. Eftari S, Mohsenzade F, Zahrakar K. The coping strategies of women dealing with infertility stress: a phenomenological approach. Journal of Woman and Family Studies 2019; 7(2):9-30.
  10. Khosrorad T, Dolatian M, Riazi H, Mahmoodi Z, Alavimajd H, Shahsavari S, et al. Comparison of lifestyle in fertile and infertile couples in Kermanshah during 2013. Iranian Journal of reproductive medicine 2015; 13(9):549.
  11. Mahboubi M, Foroughi F, Ghahramani F, Shahandeh H, Moradi S, Shirzadian T. A case--ontrol study of the factors affecting male infertility. Turkish journal of medical sciences 2014; 44(5):862-5.
  12. Keikha F, Tehraninejad ES, Rakhshkhorshid M, Afiat M, Hagholahi F, Ghasemi F. The association of the betatrophin level with metabolic and inflammatory parameters in infertile women with polycystic ovary syndrome: A case-control study. International Journal of Reproductive BioMedicine 2022; 20(1):29.
  13. Spritzer PM. Polycystic ovary syndrome: reviewing diagnosis and management of metabolic disturbances. Arquivos Brasileiros de Endocrinologia & Metabologia 2014; 58:182-7.
  14. Pembe AB, Abeid MS. Polycystic ovaries and associated clinical and biochemical features among women with infertility in a tertiary hospital in Tanzania. Tanzania journal of health research 2009; 11(4).
  15. Clayton RN, Ogden V, Hodgkinson J, Worswick L, Rodin DA, Dyer S, et al. How common are polycystic ovaries in normal women and what is their significance for the fertility of the population?. Clinical endocrinology 1992; 37(2):127-34.
  16. Ghanbari Andarieh MSc M. The serum prolactin level in infertile women with polycystic ovary syndrome. Journal of Babol University of Medical Sciences 2014; 16(8):63-8.
  17. Diamanti‐Kandarakis E, Bergiele A. The influence of obesity on hyperandrogenism and infertility in the female. Obesity Reviews 2001; 2(4):231-8.
  18. Wu S, Divall S, Nwaopara A, Radovick S, Wondisford F, Ko C, et al. Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell. Diabetes 2014; 63(4):1270-82.
  19. Tanbo T, Fedorcsak P. Endometriosis‐associated infertility: aspects of pathophysiological mechanisms and treatment options. Acta obstetricia et gynecologica Scandinavica 2017; 96(6):659-67.
  20. Dewailly D, Andersen CY, Balen A, Broekmans F, Dilaver N, Fanchin R, et al. The physiology and clinical utility of anti-Müllerian hormone in women. Human reproduction update 2014; 20(3):370-85.
  21. Zhang P, Shi Y, Gao X, Wang S, Wang J, Chen ZJ. Clinical analysis of Chinese infertility women with premature ovarian failure. Neuroendocrinology Letters 2007; 28(5):580-4.
  22. Taghavi M, Ayat-Allahi H, Dalouie MK. Evaluating the prevalence of macroprolactinemia and hyperprolactinemia and comparing their clinical and radiological signs in infertile women. Journal of Reproduction & Infertility 2007; 8(2).
  23. Foucaut AM, Faure C, Julia C, Czernichow S, Levy R, Dupont C, et al. Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women. PloS one 2019; 14(4):e0210770.
  24. Azizi A. Regulation of emotional, marital satisfaction and marital lifestyle of fertile and infertile. Rev Eur Stud 2018; 10:14.
  25. Rich-Edwards JW, Spiegelman D, Garland M, Hertzmark E, Hunter DJ, Colditz GA, et al. Physical activity, body mass index, and ovulatory disorder infertility. Epidemiology 2002; 13(2):184-90.
  26. Sharma R, Biedenharn KR, Fedor JM, Agarwal A. Lifestyle factors and reproductive health: taking control of your fertility. Reproductive biology and endocrinology 2013; 11:1-15.
  27. Chavarro JE, Toth TL, Wright DL, Meeker JD, Hauser R. Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinic. Fertility and sterility 2010; 93(7):2222-31.
  28. du Plessis SS. Fertility and pregnancy outcome among women undergoing assisted reproductive technology treatment in Windhoek, Namibia. Journal of Assisted Reproduction and Genetics 2021; 38:635-43.
  29. Jonaidy E, Noorani Sadodin S, Mokhber N, Shakeri MT. Comparing the marital satisfaction in infertile and fertile women referred to the public clinics in Mashhad in 2006-07. The Iranian Journal of Obstetrics, Gynecology and Infertility 2009; 12(1):7-16.
  30. Khanabadi M, Tabkhi F, Mahdizade F. Social issues related to the marital quality of infertile couples in Yazd: A Qualitative study. Iranian Journal of Nursing Research 2022; 17(1):5-18.
  31. Vissenberg R, Manders VD, Mastenbroek S, Fliers E, Afink GB, Ris-Stalpers C, et al. Pathophysiological aspects of thyroid hormone disorders/thyroid peroxidase autoantibodies and reproduction. Human reproduction update 2015; 21(3):378-87.
  32. Acharya S, Gowda CR. Lifestyle factors associated with infertility in a rural area: a cross-sectional study. Int J Med Sci Public Health 2017; 6(3):502-7.
  33. Javadi M, Miri N, Barikani A, Sadeghi F. The status of Smoking habit, Caffeine Intake and Body Mass Index in infertile and healthy women aged 25-40 years. The Iranian Journal of Obstetrics, Gynecology and Infertility 2017; 20(1):10-4.
  34. Harlev A, Agarwal A, Gunes SO, Shetty A, du Plessis SS. Smoking and male infertility: an evidence-based review. The world journal of men's health 2015; 33(3):143.
  35. Alvarez S. Do some addictions interfere with fertility?. Fertility and sterility 2015; 103(1):22-6.
  36. Pazandeh F, Sharghi SN, Karami NR, Alavi MH. A comparative study of psycho-social aspects between infertile & fertile women referring to a health cares center and infertility center in Tehran/2003.
  37. Esmailzadeh S, Faramarzi M, Zinalzadeh M, Nazari T. The Effects of Oral Contraceptive Pills on Fertilization in IVF Cycle. The Iranian Journal of Obstetrics, Gynecology and Infertility 2007; 10(2):39-48.
  38. West S, Lashen H, Bloigu A, Franks S, Puukka K, Ruokonen A, et al. Irregular menstruation and hyperandrogenaemia in adolescence are associated with polycystic ovary syndrome and infertility in later life: Northern Finland Birth Cohort 1986 study. Human reproduction 2014; 29(10):2339-51.
  39. He Y, Zheng D, Shang W, Wang X, Zhao S, Wei Z, et al. Prevalence of oligomenorrhea among women of childbearing age in China: A large community-based study. Women's Health 2020; 16:1745506520928617.
  40. Ghanbari E, Khazaei M, Ghahremani-Nasab M, Mehdizadeh A, Yousefi M. Novel therapeutic approaches of tissue engineering in male infertility. Cell and tissue research 2020; 380:31-42.
  41. Amini L, Kahrobaie M, Amiri-Farahani L, Haghani H. The relationship between health life style and spermogram Indicators among infertile men: preliminary data. BMC research notes 2020; 13:1-5.
The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 3
May 2024
Pages 10-20

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