Human papillomavirus and pregnancy

Document Type : Review Article

Authors

1 Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran

2 Department of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 mashhad university of medical sciences

4 Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran.

10.22038/ijogi.2024.70140.5581

Abstract

Introduction: Human papillomavirus (HPV) is the most current sexual transmitted infection. In the majority of cases, the virus disappears after 12-24 month and does not cause any specific disease. The persistence of HPV infection causes several anogenital and oropharyngeal cancer. HPV infection during pregnancy may be associated with several adverse consequences, such as premature birth and miscarriage; The purpose of the current study is to investigate the relationship between HPV infection and adverse pregnancy outcomes in different studies.

Materials and Methods: In this narrative review, PubMed and Google Scholar databases were searched using the following strategy from 2000 to 2022 to find relevant articles:

((HPV Or Papillomavirus) OR ((HPV Or Papillomavirus) AND (Pregnancy OR Diagnosis OR Treatment OR Transmission OR Symptomes OR Adverse outcomes OR Virus life cycle OR Vaccine OR Prevalence OR Epidemiology OR Risk factors OR Delivery OR Condyloma OR Acuminata Or Wart)))



Results: Immunological changes may alter the susceptibility and severity of infectious diseases, including viral infections, in pregnant women. Furthermore, increasing the steroid hormones in pregnancy period, can lead to the higher expression and transcription of the viral genome.

Conclusion: Due to the complications of HPV infection in pregnant women, such as premature birth, miscarriage, blood pressure disorders, premature membrane rupture, and fetal death, it is better to vaccinate girls at the appropriate age to avoid the adverse consequences of HPV infection during pregnancy.

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