Document Type : Original Article
Authors
1
Shahid Beheshti UMS,, Tehran,, Iran
2
Shahid Beheshti UMS, Tehran,, Iran
Abstract
Introduction: Continuation of the disease after cervical conization is a probable thing. Knowing the risk factors involved in it can facilitate the selection of treatment methods and appropriate follow-up; therefore, this study was conducted with the aim of determining the aspects related to the remaining positive margin after cervical conization.
Methods: In this retrospective cross-sectional analytical study, investigated the clinical records of all women ≥ 18 years old with intra-epithelial neoplasia (CIN) type 3 who underwent cervical conization in Imam Hossein (A) Hospital in Tehran (2017-2022), and practical factors on the condition of the internal margin after cervical conization were investigated by the enumeration method.
Results: 100 people (39.59 ± 8.60 years old, 93.0% postmenopausal, 91.0% married) were examined. There was a positive margin in 27 people (0.27%). Human papillomavirus (HPV) infection (OR = 1.810, 95% CI = 0.071-2.74, P = 0.001), old age (OR = 0.630, 95% CI = 0.092-1.02, P = 0.002) and menopause (OR = 0.815, 95% CI = 0.096-1.32, P = 0.004), respectively, with the highest chance, had increased the possibility of a positive margin after cervical conization.
Conclusion: Faster screening and identification of patients at risk of positive margin (older age, postmenopausal people, and those with HPV), especially in the early stages, and also, planning to make effective decisions in prevention and clinical management with rapid diagnosis, and timely treatment in the early stages is necessary, which is recommended.
Keywords: Conization, cervix, positive margin
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