The Relationship between Maternal Blood Group and Some Adverse Outcomes of Pregnancy

Document Type : Original Article


1 Assistant Professor, Departments of Epidemiology, Research Center for Social Factors Affecting Health, Research Institute of Health Sciences and Technology, Hamadan University of Medical Sciences, Hamadan, Iran.

2 Gynecologist, Faculty of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran.

3 Gynecologist, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

4 General Physician, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

5 Associate Professor, Department of Obstetrics and Gynecology, Infectious and Tropical Disease Research Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.


Introduction: There is a strong association between ABO blood groups and increased susceptibility to certain diseases including cardiovascular events, viral and bacterial infections, colorectal cancer, intracranial aneurysms and thromboembolic diseases. The present study was performed aimed to investigate the relationship between maternal blood groups and adverse pregnancy complications.
Methods: In this cross-sectional (descriptive-analytical) and retrospective study, the file of 400 pregnant women referred to the maternity hospital of Ali Ebn Abi Taleb Hospital of Zahedan from 2017 to 2019 were included. The variables of this study were ABO blood groups, preeclampsia, eclampsia, placental abruption, gestational diabetes mellitus, preterm labor and intrauterine growth restriction. The data collection tool included an information form in which the required information was entered. Data were analyzed by SPSS (version 22) and chi-square test. P<0.05 was considered statistically significant.
Results: Out of a total of 400 pregnant women with a mean age of 33.09±7.53 years, 153 (38.3%) had blood type O, 116 (29%) B, 97 (24.3%) A and 34 (8.5%) AB. The relationship between ABO blood groups and preeclampsia (p = 0.848), placental abruption (p = 0.833), preterm birth (p = 0.705) and intrauterine growth restriction (p = 0.214) was not statistically significant, but gestational diabetes (p=0.049) and eclampsia (p=0.039) had a significant relationship with blood groups.
Conclusion: There was no significant difference between preeclampsia, placental abruption, preterm labor and intrauterine growth restriction with ABO blood groups, but there was a significant difference between eclampsia and gestational diabetes with ABO blood groups.


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