The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

The relationship between maternal hemoglobin concentration in the first trimester of pregnancy and gestational diabetes

Document Type : Original Article

Authors
Narjes Noori 1
Alireza Ansari-Moghaddam 2
Saeed Toghi 3
1 Assistant Professor, Department of Obstetrics and Gynecology, Pregnancy Health Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
2 Professor, Department of Epidemiology, Health Promotion Research Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
3 General practitioner, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
10.22038/ijogi.2022.21134
Abstract
Introduction: Diabetes is the most common endocrine disease in pregnancy and identifying the risk factors for gestational diabetes helps to identify women who are at risk for type 2 diabetes in the future. The present study was performed aimed to determine the relationship between maternal hemoglobin concentration in the first trimester of pregnancy and gestational diabetes in pregnant women.
Methods: This retrospective study was performed on 300 cases of pregnant women who referred to medical centers of Zahedan in 2017-2019. The information checklist was used to collect demographic characteristics of research samples such as age, height, weight and number of pregnancies and deliveries, maternal hemoglobin and FBS concentrations at the first visit to the relevant centers and GCT levels in 24 to 28 weeks of pregnancy. Data were analyzed by SPSS statistical software (version 25) and Independent t-test and ANOVA tests. P<0.05 was considered statistically significant.
Results: Out of 300 women in the statistical population, 113 (37.7%) had gestational diabetes and 187 (62.3%) were healthy in terms of diabetes. Of the subjects, 103 (34.3%) had hemoglobin concentrations greater than 13, 42 (14%) had hemoglobin concentrations 12.4 to 13, 79 (26.3%) had hemoglobin concentrations between 11.6 to 12.3, and 76 (25.3%) had hemoglobin concentrations less than 11.5. The mean hemoglobin level in diabetic pregnant women was 13.71 ± 0.61 g/dl and in healthy women was 11.80 ± 0.52 g/dl, and the difference was statistically significant (P <0.001). There was also a positive and significant correlation between hemoglobin and fasting blood sugar levels (P <0.001).
Conclusion: High hemoglobin level (more than 13 g/dl) in the first trimester of pregnancy is significantly and directly related to gestational diabetes, therefore it can be considered as a risk factor for gestational diabetes.
Keywords
First trimester
Gestational diabetes
HbA1c
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 25, Issue 7
September 2022
Pages 39-44