The effect of coffee consumption on improving bowel function after abdominal hysterectomy compared to routine diet: a randomized double-blind clinical-trial

Document Type : Original Article

Authors

1 Professor, Department of Obstetrics and Gynecology, Neonatal Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Assistant professor, Department of Social Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Resident, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

4 General Practitioner, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction: Postoperative ileus causes patient discomfort, prolonged hospitalization and extra costs on health system. Few studies support the possible role of coffee consumption in reducing the incidence of ileus. The present study was performed aimed to investigate the role of coffee consumption in comparison with routine diet on improving intestinal function after abdominal hysterectomy.
Methods: This randomized double-blind clinical trial study was performed in 2020-2021 on 40 patients candidate for hysterectomy due to benign uterine disease who had referred to Imam Reza hospital in Mashhad. The patients were divided into two groups and from the day after surgery, every 6 hours for three times, patients in intervention group consumed 100 ml of coffee and patients in control group consumed 100 ml of food coloring and essence similar to coffee. The primary outcome was the time of first gas passing and secondary outcomes were the time of first bowel sound, first defecation and incidence of postoperative ileus. Data were analyzed by SPSS 27 software (version 27). P< 0.05 was considered statistically significant.
Results: There was a statistically significant difference between the two groups in comparing the time of first bowel sound (P=0.02), first gas passing (P=0.007) and first defecation (P<0.00). There was no case of severe ileus in participants. In comparison between the absence of ileus with the sum of mild and moderate ileus cases, the difference between two groups was significant (P=0.047). Comparison of hospitalization period was not significant between the two groups (P=0.24).
Conclusion: There was a statistically significant difference between the intervention and control groups in comparing the time of first bowel sound, first gas passing, first defecation and incidence of ileus. It seems that coffee consumption after abdominal hysterectomy accelerates the onset of intestinal movements and reduces the incidence of ileus.

Keywords

References

  1. Piric M, Pasic F, Rifatbegovic Z, Konjic F. The effects of drinking coffee while recovering from colon and rectal resection surgery. Medical Archives 2015; 69(6):357.
  2. Artinyan A, Nunoo-Mensah JW, Balasubramaniam S, Gauderman J, Essani R, Gonzalez-Ruiz C, et al. Prolonged postoperative ileus—definition, risk factors, and predictors after surgery. World journal of surgery 2008 ;32(7):1495-500.
  3. Doorly MG, Senagore AJ. Pathogenesis and clinical and economic consequences of postoperative ileus. Surgical Clinics 2012; 92(2):259-72.
  4. Bederman SS, Betsy M, Winiarsky R, Seldes RM, Sharrock NE, Sculco TP. Postoperative ileus in the lower extremity arthroplasty patient. The Journal of arthroplasty 2001; 16(8):1066-70.
  5. Miedema BW, Johnson JO. Methods for decreasing postoperative gut dysmotility. The lancet oncology 2003; 4(6):365-72.
  6. Lewis SJ, Egger M, Sylvester PA, Thomas S. Early enteral feeding versus “nil by mouth” after gastrointestinal surgery: systematic review and meta-analysis of controlled trials. Bmj 2001; 323(7316):773.
  7. Schneider R, Leven P, Glowka T, Kuzmanov I, Lysson M, Schneiker B, et al. A novel P2X2‐dependent purinergic mechanism of enteric gliosis in intestinal inflammation. EMBO molecular medicine 2021; 13(1):e12724.
  8. Kalff JC, Wehner S, Litkouhi B. Postoperative ileus. UpToDate, Waltkam, MA.(Accessed on October 14, 2015); 2017.
  9. Müller SA, Rahbari NN, Schmied BM, Büchler MW. Can postoperative coffee perk up recovery time after colon surgery?. Expert Review of Gastroenterology & Hepatology 2013; 7(2):91-3.
  10. Sloots CE, Felt-Bersma RJ, West RL, Kuipers EJ. Stimulation of defecation: effects of coffee use and nicotine on rectal tone and visceral sensitivity. Scandinavian journal of gastroenterology 2005; 40(7):808-13.
  11. Boekema PJ, Lo B, Samsom M, Akkermans LM, Smout AJ. The effect of coffee on gastric emptying and oro-caecal transit time. European journal of clinical investigation 2000; 30(2):129-34.
  12. Güngördük K, Özdemir İA, Güngördük Ö, Gülseren V, Gokçü M, Sancı M. Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: a randomized controlled trial. American Journal of Obstetrics and Gynecology 2017; 216(2):145-e1.
  13. McSorley ST, Steele CW, McMahon AJ. Meta-analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical-site infections in elective colorectal surgery. BJS open 2018; 2(4):185-94.
  14. Hayashi K, Tsunoda A, Shiraishi A, Kusanagi H. Quantification of the effects of coffee on postoperative ileus after laparoscopic ventral rectopexy: a randomized controlled trial. European Surgery 2019; 51(6):325-32.
  15. Ertas IE, Gungorduk K, Ozdemir A, Solmaz U, Dogan A, Yildirim Y. Influence of gum chewing on postoperative bowel activity after complete staging surgery for gynecological malignancies: a randomized controlled trial. Gynecologic oncology 2013; 131(1):118-22.
  16. Waldhausen JH, Shaffrey ME, Skenderis 2nd BS, Jones RS, Schirmer BD. Gastrointestinal myoelectric and clinical patterns of recovery after laparotomy. Annals of surgery 1990; 211(6):777.
  17. Sarawate CA, Lin SJ, Walton SM, Crawford SY, Goldstein JL. Economic burden of postoperative ileus (POI) in abdominal surgical procedures. Gastroenterology 2003; 4(124):A828.
  18. Liu SS, Wu CL. Effect of postoperative analgesia on major postoperative complications: a systematic update of the evidence. Anesthesia & Analgesia 2007; 104(3):689-702.
  19. Chapuis PH, Bokey L, Keshava A, Rickard MJ, Stewart P, Young CJ, et al. Risk factors for prolonged ileus after resection of colorectal cancer: an observational study of 2400 consecutive patients. Annals of surgery 2013; 257(5):909-15.
  20. Abraham NS, Young JM, Solomon MJ. Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer. Journal of British Surgery 2004; 91(9):1111-24.
  21. Büchler MW, Seiler CM, Monson JR, Flamant Y, Thompson‐Fawcett MW, Byrne MM, et al. Clinical trial: alvimopan for the management of post‐operative ileus after abdominal surgery: results of an international randomized, double‐blind, multicentre, placebo‐controlled clinical study. Alimentary pharmacology & therapeutics 2008; 28(3):312-25.
  22. Asao T, Kuwano H, Nakamura JI, Morinaga N, Hirayama I, Ide M. Gum chewing enhances early recovery from postoperative ileus after laparoscopic colectomy. Journal of the American College of Surgeons 2002; 195(1):30-2.
  23. Kane TD, Tubog TD, Schmidt JR. The use of coffee to decrease the incidence of postoperative ileus: a systematic review and meta-analysis. Journal of PeriAnesthesia Nursing 2020; 35(2):171-7.
  24. Müller SA, Rahbari NN, Schneider F, Warschkow R, Simon T, Von Frankenberg M, et al. Randomized clinical trial on the effect of coffee on postoperative ileus following elective colectomy. Journal of British Surgery 2012; 99(11):1530-8.
  25. Dulskas A, Klimovskij M, Vitkauskiene M, Samalavicius NE. Effect of coffee on the length of postoperative ileus after elective laparoscopic left-sided colectomy: a randomized, prospective single-center study. Diseases of the Colon & Rectum 2015; 58(11):1064-9.
  26. Gungorduk K, Paskal EK, Demirayak G, Köseoğlu SB, Akbaba E, Ozdemir IA. Coffee consumption for recovery of intestinal function after laparoscopic gynecological surgery: A randomized controlled trial. International Journal of Surgery 2020; 82:130-5.
  27. Rabiepoor S, Yas A, Navaei J, Khalkhali HR. Does coffee affect the bowel function after caesarean section?. European Journal of Obstetrics & Gynecology and Reproductive Biology 2018; 220:96-9.
  28. Rao SS, Welcher K, Zimmerman B, Stumbo P. Is coffee a colonic stimulant?. European journal of gastroenterology & hepatology 1998; 10(2):113-8.
The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 25, Issue 5
July 2022
Pages 1-10

Files

Share

How to cite

Statistics