The changes of some total antioxidant capacity and lipid peroxidation markers following the combined with high intensity interval training in sedentary postmenopausal women

Document Type : Original Article


1 M.Sc. Student of Exercise Physiology, Bonab Branch, Islamic Azad University, Bonab, Iran.

2 Associate professor, Department of Exercise Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran.

3 Assistant professor, Department of Exercise Physiology, Bonab Branch, Islamic Azad University, Bonab, Iran.


Introduction: It has been proposed that regular exercise training is effective methods to reduce the levels of oxidative stress and its disorders. Therefore, this study was performed aimed to evaluate the changes of some total antioxidant capacity and lipid peroxidation markers following the combined with high intensity interval training in sedentary postmenopausal women.
Methods: This semi-experimental study was performed  in 2020 on 45 sedentary menopause women  in Bonab city. The subjects were randomly assigned to 3 groups: high-intensity interval training, combined exercise training and control. Exercise training programs were done in 3 nonconsecutive days for twelve week. Blood samples were collected 48 hours before and after exercise training and the level of malondialdehyde (MDA) and total antioxidant capacity (TAC) were measured. Data were analyzed by SPSS software (version 24) and correlated t-test and Covariance of analysis (ANCOVA) test. P<0.05 was considered statistically significant.
Results: There were no differences between three groups in the physical physiological indices at the beginning of the study (p>0.05). The twelve week of both type of exercise training methods significantly decreased the MDA and significantly increased the TAC levels in sedentary menopause women  (p<0.05). While, there were no significant differences in these indicators during the study period in the control group. However, there were no significant difference between two exercise training methods (p>0.05). Moreover, significant correlation was observed between the changes of this markers with the changes in some of body composition indices in training groups (p<0.05).
Conclusion: Performing 12 weeks of combined and high intensity interval training can lead to increase of total antioxidant capacity and decrease lipid peroxidation indicators, therefore, it can be recommend these exercises training methods for postmenopausal women to improve oxidative stress.


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