The effect of different seasons on the rate of sperm DNA fragmentation in men

Document Type : Original Article

Authors

1 Assistant Professor, Department of Histology, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.

2 Associate Professor, Department of Obstetrics and Gynecology, Research and Clinical Center for Infertility, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.

3 Associate Professor, Department of Community Medicine, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.

4 General practitioner, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.

5 Assistant Professor, Department of Histology, Research and Clinical Center for Infertility, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.

Abstract

Introduction: Infertility and its individual and social problems are considered as one of the important problems of couples. About half of all infertility is due to male factors. Based on various studies, air temperature can affect male fertility, so the present study was conducted aimed to determine the amount of sperm DNA fragmentation of men referring to Umm Al-Banin Infertility Center in Dezful by different seasons.
Methods: In this retrospective study, the statistical population included all men who referred to the infertility center in Dezful for semen analysis between 2013 and the first half of 2020. Information about the variables including age, number of children, job, education, diseases, addiction, different seasons and sperm DNA fragmentation was collected by the researcher using a checklist. Data were analyzed using SPSS statistical software (version 24) and Chi-square and one-way ANOVA tests. P<0.05 was considered statistically significant.
Results: No significant relationship was found between sperm DNA fragmentation and different age groups, number of children, types of occupations, level of education, underlying diseases, addiction and finally different seasons and months of the year (P> 0.05).
Conclusion: According to the results, there is no relationship between different seasons and sperm DNA fragmentation in men.

Keywords

References

  1. Holstein AF, Schulze W, Davidoff M. Understanding spermatogenesis is a prerequisite for treatment. Reproductive Biology and Endocrinology 2003; 1(1):1-6.
  2. Setchell BP. The effects of heat on the testes of mammals. Animal Reproduction (AR) 2018; 3(2):81-91.
  3. Nakamura M, Namiki M, Okuyama A, Matsui T, Doi Y, Takeyama M, et al. Temperature sensitivity of human spermatogonia and spermatocytes in vitro. Archives of andrology 1987; 19(2):127-32.
  4. Peña ST, Gummow B, Parker AJ, Paris DB. Revisiting summer infertility in the pig: could heat stress-induced sperm DNA damage negatively affect early embryo development?. Animal Production Science 2016; 57(10):1975-83.
  5. Ghasemzadeh A, Nouri M, Sedghiani M, Yousefzadeh S, Fadaei Fouladi R. Effects of pentoxifylline on in vitro sperm motility and viability of infertile males with oligoasthenospermia. Iran J Obstet Gynecol Infertil 2013; 15(38):1-6.
  6. Calvo L, Dennison-Lagos L, Banks SM, Dorfmann A, Thorsell LP, Bustillo M, et al. Andrology: Acrosome reaction inducibility predicts fertilization success at in-vitro fertilization. Human Reproduction 1994; 9(10):1880-6.
  7. Benchaib M, Braun V, Lornage J, Hadj S, Salle B, Lejeune H, et al. Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique. Human Reproduction 2003; 18(5):1023-8.
  8. Dada R. Sperm DNA damage diagnostics: when and why. Translational andrology and urology 2017; 6(Suppl 4):S691-4.
  9. Zeqiraj A, Beadini S, Beadini N, Aliu H, Gashi Z, Elezaj S, et al. Male infertility and sperm DNA fragmentation. Open access Macedonian journal of medical sciences 2018; 6(8):1342-5.
  10. Kim GY. What should be done for men with sperm DNA fragmentation? Clinical and experimental reproductive medicine 2018; 45(3):101-109.
  11. Christensen P, Humaidan P. Testing of sperm DNA damage and clinical recommendations. Translational andrology and urology 2017; 6(Suppl 4):S607.
  12. Panner Selvam MK, Agarwal A. A systematic review on sperm DNA fragmentation in male factor infertility: laboratory assessment. Arab Journal of Urology 2018; 16(1):65-76.
  13. Nabi A, Khalili M, Halvaei I, Anbari F. Apoptosis Will Be Increased After 2H Incubation Of Human Sperm At 37OC. Journal Of Cell & Tissue 2014; 4(4):415-23.
  14. Stone BA, Seamark RF. Effects of acute and chronic testicular hyperthermia on levels of testosterone and corticosteroids in plasma of boars. Animal Reproduction Science 1984; 7(5):391-403.
  15. Stone BA. Heat induced infertility of boars: the inter-relationship between depressed sperm output and fertility and an estimation of the critical air temperature above which sperm output is impaired. Animal Reproduction Science 1982; 4(4):283-99.
  16. Suriyasomboon A, Lundeheim N, Kunavongkrit A, Einarsson S. Effect of temperature and humidity on reproductive performance of crossbred sows in Thailand. Theriogenology 2006; 65(3):606-28.
  17. Peña ST, Stone F, Gummow B, Parker AJ, Paris DB. Tropical summer induces DNA fragmentation in boar spermatozoa: implications for evaluating seasonal infertility. Reproduction, Fertility and Development 2019; 31(3):590-601.
The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 24, Issue 13
February 2022
Pages 29-34

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