The effect of Salvia hydrangea and Mefenamic acid on postpartum pain; Randomized clinical trial

Document Type : Original Article

Authors

1 M.Sc. student of Midwifery, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Instructor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Assistant professor, Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Assistant professor, Department of Biostatics, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.

Abstract

Introduction: Postpartum pain is one of the common postpartum problems that has adverse consequences for both mother and infant. The side effects of chemical drugs have led to the tendency to use herbal medicines to reduce postpartum pain. This study was performed with aim to investigate the effect of Saliva hydrangea capsule on postpartum pain.
Methods: This double-blind randomized clinical trial study was performed in 2018 on 100 mothers that 2 hours had passed from their normal vaginal delivery and had severity of moderate to severe postpartum pain based on visual pain scale (VAS). The women were randomly assigned in two groups: Saliva hydrangea+mefenamic acid and placebo+mefenamic acid. The capsules were used every 6 hours. The intensity and duration of pain were recorded before and one hour after the intervention by VAS. Data were analyzed by SPSS software (version 21) and independent- t and paired t-test, Mann-Whitney U test and repeated measures. P<0.05 was considered statistically significant.
Results:After the end of the intervention, the mean of pain score in Saliva hydrangea group (0.32 ± 0.12) was significantly lower than placebo group (0.92 ± 3.60) (p <0.05). Pain relief time interval in the intervention group after the first dose (0.25 ± 1.36) and after the final dose (0.48 ± 1.30) significantly decreased compared to the placebo group after the first dose (0.81 ± 3.27) and after the final dose (0.88 ± 3.62) (p <0.05).
Conclusion: The combination of Saliva hydrangea and mefenamic acid is more effective on the severity of postpartum pain and the time required to relieve pain compared to mefenamic acid alone, and as a herbal drug can decrease the severity of postpartum pain.

Keywords

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 24, Issue 11
December 2021
Pages 70-78

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