Document Type : Original Article
Assistant Professor, Department of General Surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Assistant Professor, Department of Infectious Diseases, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Introduction: Post-mastectomy infection can dramatically increase the duration of recovery. Considering the potential role of vitamin D in preventing infection, this study was performed with aim to compare serum levels of post-mastectomy vitamin D in women with and without postoperative infection.
Methods: This case-control study was performed on 50 women after mastectomy at Tabriz Imam Reza Hospital in 2017-2018. Demographic information and vitamin D levels (taking blood samples) were included in a researcher-made instrument containing disease-related information. Data were analyzed by SPSS software (version 20) and independent t-test and Chi-square tests. P< 0.05 was considered statistically significant.
Results: The mean of vitamin D in the infected group was 27.33 ±2.41 and in the uninfected group was 49.55±4.11 (p=0.004). Also, most patients in the infected group (48%) had vitamin D deficiency, while most subjects in the uninfected group (60%) had normal vitamin D that the difference between the two groups was significant (p=0.003).
Conclusion: Low levels of vitamin D increase the risk of infection after mastectomy in women with cancer.