مجله زنان، مامایی و نازایی ایران

مجله زنان، مامایی و نازایی ایران

بررسی تأثیر کرم واژینال فلفل آبی بر عملکرد جنسی زنان یائسه

نوع مقاله : اصیل پژوهشی

نویسندگان
مهدیه قربانی 1
دکتر مینا ایروانی 2
دکتر اسکندر مقیمی پور 3
دکتر الهام مراغی 4
1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.
2 دانشیار گروه مامایی، مرکز تحقیقات یائسگی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.
3 استاد گروه فارماسیوتیکس، مرکز تحقیقات گیاهان دارویی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.
4 استادیار گروه اپیدمیولوژی و آمار زیستی، دانشکده بهداشت، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.
10.22038/ijogi.2025.84506.6288
چکیده
مقدمه: کاهش سطح استروژن در دوران یائسگی موجب تغییراتی در بافت دستگاه تناسلی می‌شود. اختلال عملکرد جنسی، یکی از مشکلات شایع زنان یائسه می‌باشد. مطالعه حاضر با هدف بررسی تأثیر کرم واژینال فلفل آبی بر عملکرد جنسی در زنان یائسه انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی دوسوکور در سال 1403 بر روی 111 زن یائسه 65-45 ساله در شهرستان اهواز انجام شد. افراد به سه گروه کرم واژینال فلفل آبی بر پایه روغن نارگیل و کنجد، دارونما و استروژن کونژوگه تقسیم شده و به‌مدت 12 هفته تحت درمان قرار گرفتند. ویزیت در هفته ­های 4، 8 و 12 پس از پایان درمان انجام شد. برای جمع‌آوری داده­ ها از شاخص عملکرد جنسی زنان استفاده شد. تجزیه و تحلیل داده­ ها با استفاده از نرم‌افزار آماری SPSS (نسخة 25) و آزمون‌های شاپیروویلک، کای اسکوئر، آنالیز واریانس یک‌طرفه و آنالیز واریانس با اندازه ­گیری تکراری انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته­ ها: بعد از درمان، نمره عملکرد جنسی زنان در گروه فلفل آبی در مقایسه با گروه پلاسبو به‌طور معنی‌داری افزایش یافت (0001/0>p)، اما در مقایسه با گروه استروژن کونژوگه، اختلاف آماری معنی‌داری مشاهده نشد (05/0<p).
نتیجه ­گیری: کرم واژینال فلفل آبی در بهبود عملکرد جنسی و ابعاد آن در زنان یائسه مشابه با درمان استاندارد مؤثر می­ باشد، لذا می­ تواند به‌عنوان یک جایگزین درمانی غیرهورمونی برای بهبود اختلال مذکور در نظر گرفته شود.
کلیدواژه‌ها
عملکرد جنسی
فلفل آبی
کنجد
نارگیل
یائسگی
موضوعات

عنوان مقاله English

The Effect of Persicaria Hydropiper Vaginal Cream on Sexual Function of Postmenopausal Women

نویسندگان English

Mahdieh Ghorbani 1
Mina Iravani 2
Eskandar Moghimipour 3
Elham Maraghi 4
1 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Ahvaz Jundishapur of Medical Sciences, Ahvaz, Iran.
2 Associate Professor, Department of Midwifery, Menopause Research Center, School of Nursing and Midwifery, Ahvaz Jundishapur of Medical Sciences, Ahvaz, Iran.
3 Professor, Department of Pharmaceutics, Medicinal Plants Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
4 Assistant Professor, Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
چکیده English

Introduction: Decreasing estrogen levels during menopause cause changes in the tissues of the reproductive system. Sexual dysfunction is a common problem in menopausal women. This study was conducted with aim to investigate the effect of Persicaria hydropiper vaginal cream on sexual function in menopausal women.
Methods: This double-blind clinical trial study was conducted in 2024 on 111 postmenopausal women aged 45-65 years in Ahvaz city. Subjects were divided into three groups: Persicaria hydropiper vaginal cream based on coconut and sesame oil, placebo, and conjugated estrogen, and were treated for 12 weeks. Visits were made at weeks 8, 12, and 4 after the end of treatment. Female Sexual Function Index was used to collect data. Data were analyzed using SPSS software (version 25) and Shapiro-Wilk test, chi-square, one-way analysis of variance, and repeated-measures analysis of variance. P < 0.05 was considered significant.
Results: After treatment, the women sexual function score in the Persicaria hydropiper group significantly increased compared to the placebo group (P<0.0001), but no statistically significant difference was observed compared to the conjugated estrogen group (P>0.05).
Conclusion: Persicaria hydropiper vaginal cream is as effective as standard treatment in improving sexual function and its dimensions in menopausal women. Therefore, it can be considered as a non-hormonal alternative treatment for improving the aforementioned disorder.

کلیدواژه‌ها English

Coconut
Menopause
Persicaria Hydropiper
Sesame
Sexual Function
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مجله زنان، مامایی و نازایی ایران
دوره 28، شماره 6
شهریور 1404
صفحه 51-65