بررسی تغییرات سطوح برخی شاخص‌های پراکسیداسیون لیپیدی و آنتی‌اکسیدانی تام سرم زنان یائسه غیرفعال به‌دنبال تمرینات ترکیبی و تناوبی شدید

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد فیزیولوژی ورزشی، واحد بناب، دانشگاه آزاد اسلامی، بناب، ایران.

2 دانشیار گروه فیزیولوژی ورزشی، واحد مهاباد، دانشگاه آزاد اسلامی، مهاباد، ایران.

3 استادیار گروه فیزیولوژی ورزشی، واحد بناب، دانشگاه آزاد اسلامی، بناب، ایران.

چکیده

مقدمه: پیشنهاد شده است که انجام فعالیت‌های ورزشی منظم می‌تواند روش مؤثری جهت کاهش سطوح استرس اکسیداتیو و اختلالات ناشی از آن باشد. بنابراین مطالعه حاضر با هدف بررسی تغییرات سطوح برخی شاخص‌های پراکسیداسیون لیپیدی و آنتی‌اکسیدانی تام سرم زنان یائسه غیرفعال به‌دنبال تمرینات ترکیبی و تناوبی شدید انجام شد.
روش‌کار: این مطالعه نیمه­تجربی در سال 1399 بر روی 45 زن یائسه بی‌تحرک در شهرستان بناب انجام شد. افراد به‌طور تصادفی، در یکی از سه گروه تمرینات تناوبی شدید، تمرینات ترکیبی و گروه کنترل قرار گرفتند. برنامه تمرینی 3 روز در هفته و به‌مدت 12 هفته انجام شد. نمونه‌گیری خون 48 ساعت قبل و بعد از دوره تمرینات گرفته شد و سطوح سرمی شاخص‌های مالون دی‌آلدئید (MDA) و ظرفیت آنتی‌اکسیدان تام (TAC) مورد اندازه‌گیری و آنالیز قرار گرفت. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 24) و آزمون‌های آماری تی همبسته و آنالیز کوواریانس در سطح معناداری 05/0 انجام شد.
یافته‌ها: در مقادیر شاخص‌های جسمانی و فیزیولوژیکی قبل از اجرای پروتکل تمرینی، تفاوت معنی‌داری بین سه گروه مورد مطالعه وجود نداشت (05/0<p). هر دو روش تمرینات ترکیبی و تناوبی شدید به‌مدت 12 هفته باعث کاهش معنا‌دار سطوح MDA و همچنین افزایش معنادار TAC در زنان یائسه بی‌تحرک شد (05/0>p)، در حالی‌که نتایج گروه کنترل نشان‌دهنده عدم تغییر معنادار این شاخص‌ها زمان انجام پژوهش بود (05/0‌<p). همچنین، تفاوت معناداری بین دو گروه تمرینی در هیچ‌کدام از متغیرهای مذکور وجود نداشت (05/0˃p). به‌علاوه، بین دامنه تغییرات سطوح این شاخص‌ها با تغییرات برخی از شاخص‌های ترکیب بدن در گروه‌های تمرین همبستگی معناداری مشاهده شد (05/0>p).
نتیجه‌گیری: انجام روش‌های تمرین ترکیبی و تناوبی شدید به‌مدت 12 هفته می‌تواند باعث افزایش سطوح ظرفیت آنتی‌اکسیدانی تام سرمی و کاهش نشانگر پراکسیداسیون لیپیدی شود، لذا می‌توان انجام این روش‌های تمرینی را به زنان یائسه بی‌تحرک جهت بهبود وضعیت استرس اکسیداتیو توصیه نمود.

کلیدواژه‌ها

عنوان مقاله [English]

The changes of some total antioxidant capacity and lipid peroxidation markers following the combined with high intensity interval training in sedentary postmenopausal women

نویسندگان [English]

  • Sara Akhtegan 1
  • Sirvan Atashak 2
  • Reza Roshdi Bonab 3
1 M.Sc. Student of Exercise Physiology, Bonab Branch, Islamic Azad University, Bonab, Iran.
2 Associate professor, Department of Exercise Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran.
3 Assistant professor, Department of Exercise Physiology, Bonab Branch, Islamic Azad University, Bonab, Iran.
چکیده [English]

Introduction: It has been proposed that regular exercise training is effective methods to reduce the levels of oxidative stress and its disorders. Therefore, this study was performed aimed to evaluate the changes of some total antioxidant capacity and lipid peroxidation markers following the combined with high intensity interval training in sedentary postmenopausal women.
Methods: This semi-experimental study was performed  in 2020 on 45 sedentary menopause women  in Bonab city. The subjects were randomly assigned to 3 groups: high-intensity interval training, combined exercise training and control. Exercise training programs were done in 3 nonconsecutive days for twelve week. Blood samples were collected 48 hours before and after exercise training and the level of malondialdehyde (MDA) and total antioxidant capacity (TAC) were measured. Data were analyzed by SPSS software (version 24) and correlated t-test and Covariance of analysis (ANCOVA) test. P<0.05 was considered statistically significant.
Results: There were no differences between three groups in the physical physiological indices at the beginning of the study (p>0.05). The twelve week of both type of exercise training methods significantly decreased the MDA and significantly increased the TAC levels in sedentary menopause women  (p<0.05). While, there were no significant differences in these indicators during the study period in the control group. However, there were no significant difference between two exercise training methods (p>0.05). Moreover, significant correlation was observed between the changes of this markers with the changes in some of body composition indices in training groups (p<0.05).
Conclusion: Performing 12 weeks of combined and high intensity interval training can lead to increase of total antioxidant capacity and decrease lipid peroxidation indicators, therefore, it can be recommend these exercises training methods for postmenopausal women to improve oxidative stress.

کلیدواژه‌ها [English]

  • Combined training
  • High intensity interval training
  • Malondialdehyde
  • Postmenopausal women
  • Total antioxidant capacity

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مجله زنان، مامایی و نازایی ایران
دوره 24، شماره 13
اسفند 1400
صفحه 70-79

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